Anaplastic large-cell lymphoma with atypical chromosomal translocation t(2;5) and hypophyseal tumor
Source: Upsala Journal of Medical Sciences, Volume 115, Number 4, November 2010 , pp. 287-290(4)
Publisher: Informa Healthcare
Anaplastic large T-cell lymphoma (ALCL) is frequently associated with the t(2;5)(p23;q35). Here, we report a case of ALCL with an atypical translocation of t(2;5)(p24;q13) and other complex translocations. This complex abnormal karyotype may result in chemotherapy resistance and a poor outcome. Interestingly, a hypophyseal tumor was detected simultaneously by magnetic resonance imaging in this case. We think it is probable that the tumor in the hypophysis might be associated with the ALCL.
Document Type: Case Report
Affiliations: 1: 1Department of Hematology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China 2: 2Institute of Hematology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China
Publication date: November 1, 2010