Ambient Exposure to Criteria Air Pollutants and Risk of Death from Bladder Cancer in Taiwan
Source: Inhalation Toxicology, Volume 21, Number 1, January 2009 , pp. 48-54(7)
Publisher: Informa Healthcare
Abstract:To investigate the relationship between air pollution and risk of death from bladder cancer, the authors conducted a matched case-control study using deaths that occurred in Taiwan from 1995 through 2005. Data on all eligible bladder cancer deaths were obtained from the Bureau of Vital Statistics of the Taiwan Provincial Department of Health. The control group consisted of people who died from causes other than cancer or diseases associated with genitourinary problems. The controls were pair matched to the cases by sex, year of birth, and year of death. Each matched control was selected randomly from the set of possible controls for each case. Classification of exposure to municipality air pollution was based on the measured levels of nitrogen dioxide and sulfur dioxide. The results of the present study show that there is a significant positive association between the levels of air pollution and bladder cancer mortality. The adjusted odds ratios (95% confidence interval) were 1.37 (1.03-1.82) for the group with medium air pollution level and 1.98 (1.36-2.88) for the group with high air pollution level when compared to the group with the low air pollution level. Trend analyses showed statistically significant trend in risk of death from bladder cancer with increasing air pollution level. The findings of this study warrant further investigation of the role of air pollutants in the etiology of bladder cancer.
Document Type: Research Article
Affiliations: 1: Institute of Occupational Safety and Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung,Kaohsiung and Department of Pediatrics, Kaohsiung Municipal Min-Sheng Hospital, Kaohsiung 2: Department of Health Care Administration, I-Shou University, Kaohsiung County 3: Department of Pharmacology, College of Medicine, Kaohsiung Medical University, Kaohsiung 4: Graduate Institute of Environmental Health, China Medical University, Taichung 5: Section of Neonatology, Department of Pediatrics, Kaohsiung Chang-Gung Medical Center, Kaohsiung County 6: Faculty of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan
Publication date: January 1, 2009