Azathioprine-induced squamous cell carcinoma of the kidney

Authors: Nair, Balagopal; Sukumar, Sudhir; Poolari, Ginil Kumar; Appu, Thomas

Source: Scandinavian Journal of Urology and Nephrology, Volume 41, Number 2, 2007 , pp. 173-175(3)

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Abstract:

Immunosuppressive therapy with azathioprine has been documented to cause squamous cell carcinoma (SCC) at various sites. We report possibly the first case of SCC of the kidney in a young male who received azathioprine for a long time. Discontinuation of azathioprine post-radical nephrectomy probably increased the patient's metastatic disease-free survival.

Keywords: Azathioprine; carcinogen; immunosuppression; nephrectomy; renal pelvis; squamous cell carcinoma

Document Type: Research article

DOI: http://dx.doi.org/10.1080/00365590601017394

Affiliations: 1: Department of Urology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India

Publication date: 2007-01-01

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