Behçet's disease in Moroccan children: a report of 12 cases

Authors: F Allali¹; A Benomar²; A Karim³; N Lazrak¹; Z Mohcine³; M El Yahyaoui²; T Chkili²; N Hajjaj-Hassouni¹

Source: Scandinavian Journal of Rheumatology, Volume 33, Number 5, October 2004 , pp. 362-363(2)

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Abstract:

We report 12 cases of Behçet's disease (BD) in children. The mean age of symptom onset was 12.4 years. Four patients (33.3%) had a past familial history of BD. Clinical manifestations were: oral aphtosis (n=12), genital aphtosis (n=9), ocular involvement (n=9), neuro-Behçet (n=6), venous thrombosis (n=4), articular involvement (n=3), and entero-Behçet (n=1). All patients but one were initially treated with steroids; three cases with ocular involvement were treated with chlorambucil; and three other cases of neuro-Behçet were treated with cyclophosphamide. After a mean follow-up of 4 years, four patients with neurological involvement developed steroid-dependence with recurrence of symptoms. Four patients had optic atrophy with blindness.

Keywords: Behçet's disease; children

Document Type: Research article

DOI: http://dx.doi.org/10.1080/03009740410005980

Affiliations: 1: Rheumatology B Department El Ayachi Hospital 2: Ophthalmology A Department 3: Neurology Department, Specialities Hospital Rabat-Sale University Hospital Morocco

Publication date: 2004-10-01

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