Air bag injury as a cause of inflammatory myofibroblastic pseudotumour of the subglottic larynx progressing to myositis ossificans

Authors: Alaani, A.¹; Hogg, R.¹; Warfield, A. T.²; Olliff, J.³; Jennings, C.¹

Source: Acta Oto-Laryngologica, Volume 125, Number 6, June 2005 , pp. 674-677(4)

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Abstract:

Inflammatory myofibroblastic pseudotumour (IMFPT) is a rare condition. The clinical presentation can be indistinguishable from that of a malignant neoplasm. The most frequently affected organ is the lung; a much less common site is the larynx and subglottic involvement is particularly rare. Trauma is purportedly one potential aetiological factor, although there have been no previous reports of IMFPT occurring in the larynx secondary to external laryngeal trauma. We present a case of IMFPT of the subglottis which occurred subsequent to external trauma of the neck sustained during air bag inflation in a road traffic accident. This mechanism has not been previously reported. Furthermore, the lesion progressed uniquely to show myositis ossificans-like maturation over time. The patient was ultimately treated by means of complete local excision.

Keywords: Laryngeal neoplasia; laryngofissure; myofibroblast; myositis ossificans; pseudotumour; subglottic region

Document Type: Research article

DOI: http://dx.doi.org/10.1080/00016480510026872

Affiliations: 1: Department of ENT, Queen Elizabeth Hospital, Birmingham, UK 2: Department of Histopathology, Medical School, University of Birmingham and, Birmingham, UK 3: Department of Radiology, Queen Elizabeth Hospital, Birmingham, UK

Publication date: 2005-06-01

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