Localization of Heme Oxygenase-2 in the Canine Larynx
Authors: Koike, Shinobu; Uno, Toshiyuki; Bamba, Hitoshi; Shogaki, Kazuhiro; Hirota, Ryuichi; Hisa, Yasuo
Source: Acta Oto-Laryngologica, Volume 121, Number 2, 1 March 2001 , pp. 315-317(3)
Publisher: Informa Healthcare
Abstract:The localization of heme oxygenase-2 (HO-2) in the larynx of the dog was investigated using immunohistochemistry. HO-2-positive cells were seen among neurons in intralaryngeal ganglia. Nerve fibers positive to HO-2 immunohistochemistry were seen surrounding laryngeal glands and arterioles and also in the adventitia of arterioles. HO-2-positive fibers were also seen running parallel to the mucosa in the lamina propria but no positive fibers were seen in the epithelium. Some of the intramuscular neurons found in the intrinsic laryngeal muscles were HO-2-positive, although no positive motor fibers were seen, and the neuromuscular junctions were also HO-2-negative. The results implicate the participation of HO-2-in the parasympathetic innervation of the larynx.
Document Type: Research Article
Affiliations: Department of Otolaryngology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Publication date: 1 March 2001