Intravascular Lymphoma Mimicking a Vogt-Koyanagi-Harada Disease
Source: Ocular Immunology and Inflammation, Volume 19, Number 2, April 2011 , pp. 132-134(3)
Publisher: Informa Healthcare
Abstract:Purpose: To report a case of intravascular lymphoma (IVL) mimicking a Vogt-Koyanagi-Harada disease (VKH).
Design: Case report.
Methods: A 38-year-old man was referred for blurred vision, headache, and hearing loss. Examination demonstrated vitritis and subretinal detachments in each eye. Cerebral fluid analysis showed lymphocytic meningitis. Cerebral MRI was normal. A diagnosis of VKH disease was made.
Results: Steroid treatment was introduced, after which all symptoms disappeared. Six months later, the patient returned with paraplegia and confusion. Cerebral MRI revealed hypodense periventricular lesions. A stereotaxic biopsy confirmed the diagnosis of IVL. The patient died a few months later.
Conclusion: IVL may have many revealing aspects, including ophthalmologic symptoms.
Document Type: Research Article
Affiliations: 1: 1Department of Ophthalmology, Centre Hospitalier Universitaire, CHU-Nancy, France 2: 2Department of Ophthalmology, Pitiéé-Salpêêtrièère Hospital, Paris, France 3: 3Department of Internal Medicine, Centre Hospitalier Universitaire, CHU-Nancy, France 4: 4Department of Neuropathology, Pitiéé-Salpêêtrièère Hospital, Paris, France 5: 5Department of Neurology, Pitiéé-Salpêêtrièère Hospital, Paris, France
Publication date: 2011-04-01