Clinical Manifestations of Ocular Toxoplasmosis
Source: Ocular Immunology and Inflammation, Volume 19, Number 2, April 2011 , pp. 91-102(12)
Publisher: Informa Healthcare
Abstract:Clinical manifestations of ocular toxoplasmosis are reviewed. Findings of congenital and acute acquired ocular toxoplasmosis include retinal scars, white-appearing lesions in the active phase often associated with vitritis. Complications can include fibrous bands, secondary serous or rhegmatogenous retinal detachments, optic neuritis and neuropathy, cataracts, increased intraocular pressure during active infection, and choroidal neovascular membranes. Recurrences in untreated congenital toxoplasmosis occur in teenage years. Manifestations at birth are less severe, and recurrences are fewer in those who were treated promptly early in the course of their disease in utero and in the first year of life. Severe retinal involvement is common at diagnosis of symptomatic congenital toxoplasmosis in the United States and Brazil. Acute acquired infections also may be complicated by toxoplasmic retinochoroiditis, with recurrences most common close to the time of acquisition. Suppressive treatment can reduce recurrent disease.
Document Type: Research Article
Affiliations: 1: 1Universitéé Paris Descartes, Service d’’Ophtalmologie, Hôôpital Cochin, Paris, France 2: 2New York Eye and Ear Institute, New York University, New York, New York, USA 3: 3Northwestern University Children’’s Memorial Hospital and the University of Chicago, Chicago, Illinois, USA 4: 4Northshore University Health System and the University of Chicago, Chicago, Illinois, USA 5: 5The University of Chicago, Chicago, Illinois, USA
Publication date: April 1, 2011