Early Versus Delayed Correction of Infantile Strabismus in Macaque Monkeys: Effects on Long-Term Eye Alignment
Source: Neuro-Ophthalmology, Volume 31, Numbers 5-6, September 2007 , pp. 167-169(3)
Publisher: Informa Healthcare
Abstract:Purpose: To determine how the duration of infantile strabismus influences the eventual eye alignment. Methods: Six infant macaques were fitted with prisms, which were removed after 3 weeks (wks.), 3 months (mos.), or 6 mos. Two control monkeys wore plano lenses. Eye alignment was measured using search coils. Results: Longer duration of infantile strabismus is correlated with a more severe misalignment. The strabismus in the 6-mos. group was 96% greater than that in the 3-mos. group, which, in turn, was 25 times greater than that in the 3-wks group (p < 0.05). Conclusions: Longer duration of infantile strabismus causes larger-angle esotropia. Early correction of infantile strabismus is supported.
Document Type: Research Article
Affiliations: 1: Faculty of Medicine, Queen's University, Ontario, Canada 2: Departments of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri,Departments of Pediatrics, Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri 3: Departments of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri 4: Yerkes Regional Primate Research Center, Atlanta, Georgia 5: Department of Ophthalmology and Vision Sciences, University of Toronto, Ontario, Canada
Publication date: September 1, 2007