Rupture of an unscarred uterus with misoprostol induction: case report and review of the literature

Authors: Khabbaz, A. Y.; Usta, I. M.; El-Hajj, M. I.; Abu-Musa, A.; Seoud, M.; Nassar, A. H.

Source: Journal of Maternal-Fetal Medicine, Volume 10, Number 2, 1 April 2001 , pp. 141-145(5)

Publisher: Informa Healthcare

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Abstract:

Uterine rupture is a serious and often tragic complication that is life threatening to both mother and child. It occurs at a frequency of around 1% in patients with a previously scarred uterus. Rupture of an unscarred uterus is an unexpected and devastating complication of pregnancy. With the increased use of misoprostol as a labor-inducing agent, cases of rupture of an unscarred uterus following its use have been published in the literature. We report a case of uterine rupture in a multigravid woman with an intrauterine fetal death at 29 weeks' gestation whose labor was induced with misoprostol. A review of all cases of uterine rupture with misoprostol induction is also included. Excessive doses of misoprostol should be used with extreme caution in multiparous women and in patients with a previously scarred uterus even in the context of intrauterine fetal death or termination of pregnancy.

Keywords: LABOR INDUCTION; MISOPROSTOL; UNSCARRED UTERUS; UTERINE RUPTURE

Document Type: Case Report

Affiliations: Department of Obstetrics and Gynecology, American University of Beirut, Medical Center, Beirut, Lebanon

Publication date: April 1, 2001

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