Low Achieved Diastolic Pressure in Tightly Controlled Mid-Older Hypertensive Subjects Is Associated With Favorable Arterial Properties

Authors: Yaron, Marianna; Osher, Etty; Izkhakov, Elena; Rosenfeld, Joseph B.; Stern, Naftali

Source: Clinical and Experimental Hypertension, Volume 34, Number 5, August 2012 , pp. 321-327(7)

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Abstract:

Low diastolic blood pressure (DBP) is commonly seen in well-controlled hypertensive subjects. We evaluated arterial properties in 53 hypertensive subjects with low on-treatment DBP (<70 mm Hg; LODP), 54 subjects with normal BP and spontaneously low DBP (SLDP), and 52 treated hypertensive subjects with DBP ≥70 mm Hg (HNDP). The two measures of large artery rigidity, pulse wave velocity and augmentation index, were similar in LODP and SLDP groups. In contrast, the HNDP group had higher PWV and the lowest large and small artery compliance in comparison with all other groups. Low on-treatment DBP is associated with favorable arterial properties in mid-older hypertensive patients.

Keywords: arterial stiffness; hypertension; low diastolic blood pressure; pulse wave velocity

Document Type: Research article

DOI: http://dx.doi.org/10.3109/10641963.2011.628728

Affiliations: 1: 1Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

Publication date: 2012-08-01

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