Journal of Enzyme Inhibition and Medicinal Chemistry

Proceedings of the 17th annual conference of the Groupement des Pharmacochimistes de l'Arc Atlantique (GP2A) and the 22nd “Journées Franco-Belges de Pharmacochimie”
pp. 151-151(1)

Description and assessment of a model for GSK-3β database virtual screening
pp. 152-157(6)
Authors: Ventimila, Nadege; Dupont, Pierre-Yves; Laguerre, Michel; Dessolin, Jean

Quinazoline-urea, new protein kinase inhibitors in treatment of prostate cancer
pp. 158-171(14)
Authors: Garofalo, Antonio; Goossens, Laurence; Lemoine, Amelie; Farce, Amaury; Arlot, Yannick; Depreux, Patrick

Semisynthesis of α-methyl-γ-lactones and in vitro evaluation of their activity on protein farnesyltransferase
pp. 172-179(8)
Authors: Pinel, Benoit; Dubois, Joëlle; Séraphin, Denis; Richomme, Pascal

Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects
pp. 180-194(15)
Authors: Barrett, Irene; Carr, Miriam; O'Boyle, Niamh; Greene, Lisa M.; J. S. Knox, Andrew; Lloyd, David G.; Zisterer, Daniela M.; Meegan, Mary J.

Prediction of acute toxicity in fish by using QSAR methods and chemical modes of action
pp. 195-203(9)
Authors: Lozano, Sylvain; Lescot, Elodie; Halm, Marie-Pierre; Lepailleur, Alban; Bureau, Ronan; Rault, Sylvain

Synthesis and evaluation of the antiproliferative activity of novel pyrrolo[1,2-a]quinoxaline derivatives, potential inhibitors of Akt kinase. Part II
pp. 204-215(12)
Authors: Desplat, Vanessa; Moreau, Stephane; Gay, Aurore; Fabre, Solene Belisle; Thiolat, Denis; Massip, Stephane; Macky, Gregory; Godde, Frederic; Mossalayi, Djavad; Jarry, Christian; Guillon, Jean

Antiproliferative effect on HepaRG cell cultures of new calix[4]arenes
pp. 216-227(12)
Authors: Rouge, Pascal; Pires, Viviane Silva; Gaboriau, François; Dassonville-Klimpt, Alexandra; Guillon, Jean; Nascimento, Sophie Da; Leger, Jean-Michel; Lescoat, Gerard; Sonnet, Pascal

Erymildbraedin A and B, two novel cytotoxic dimethylpyrano-isoflavones from the stem bark of Erythrina mildbraedii: evaluation of their activity toward endocrine cancer cells
pp. 228-233(6)
Authors: Tchokouaha, Ruben F.; Alexi, Xanthippi; Chosson, Elizabeth; Besson, Thierry; Skaltsounis, Alexios-Leandros; Seguin, Elisabeth; Alexis, Michael N.; Wandji, Jean

A FRET-based microplate assay for human protein kinase CK2, a target in neoplastic disease
pp. 234-239(6)
Authors: Gratz, Andreas; Götz, Claudia; Jose, Joachim

3D-QSAR, molecular docking studies, and binding mode prediction of thiolactomycin analogs as mtFabH inhibitors
pp. 240-249(10)
Authors: Lu, Xiaoyun; Chen, Yadong; You, Qidong

Human polymerase α inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives
pp. 250-265(16)
Authors: Höltje, Monika; Richartz, Anja; Zdrazil, Barbara; Schwanke, Anja; Dugovic, Branislav; Murruzzu, Caterina; Reißig, Hans-Ulrich; Korting, Hans Christian; Kleuser, Burkhard; Höltje, Hans-Dieter; Schäfer-Korting, Monika

Synthesis and biological evaluation of some novel 6-aryl-2-(p-sulfamylphenyl)-4,5-dihydropyridazin-3(2H)-ones as anti-cancer, antimicrobial, and anti-inflammatory agents
pp. 266-271(6)
Authors: Ahmad, Shamim; Rathish, I. G.; Bano, Sameena; Alam, M. S.; Javed, Kalim

Potent inhibitory effects of benzyl and p-xylidine-bis dithiocarbamate sodium salts on activities of mushroom tyrosinase
pp. 272-281(10)
Authors: Amin, E.; Saboury, A. A.; Mansuri-Torshizi, H.; Moosavi-Movahedi, A. A.

The effect of substituted thiophene and benzothiophene derivates on PPARγ expression and glucose metabolism
pp. 282-289(8)
Authors: Shao, Huayi; Li, Dong; Yang, Yi; Guo, Hui-Fang; Liu, Zong-Ying; Si, Shu-Yi; Yang, Ze; Li, Zhuo-Rong

Inhibitory effects of thioethers on fatty acid synthase and 3T3-L1 cells
pp. 290-295(6)
Authors: Sun, Xue-Bing; Zhao, Jiong; Ma, Xiao-Feng; Tian, Wei-Xi

Urease inhibitors from Hypericum oblongifolium WALL.
pp. 296-299(4)
Authors: Arfan, Mohammad; Ali, Mumtaz; Ahmad, Habib; Anis, Itrat; Khan, Ajmal; Choudhary, M. Iqbal; Shah, Muhammad Raza