Authors: Halve, Anand; Dubey, Pushp Kant; Kankoriya, Amit; Tiwari, Kiran

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 24, Number 1, February 2009 , pp. 176-180(5)

Publisher: Informa Healthcare

Abstract:

A new series of 4-phenyldiazenyl 2-(phenylimino methyl) phenols were synthesized by the condensation of 5-[(2-chloro phenyl) diazenyl] 2-hydroxybenzaldehyde with different substituted aromatic amines and sulphonamides. All the synthesized compounds were screened in-vitro for their antibacterial activity against different human pathogens viz: B. anthracis, E.coli, S. aureus, S. typhimurium, and P. aeruginosa using disk diffusion assay. All the compounds exhibited considerable inhibition against the bacteria tested.

Keywords: Antibacterial screening; imines; multidrug resistant; disc diffusion; 2-phenyldiazenyl 2-(phenylimino methyl) phenols

Document Type: Research article

DOI: http://dx.doi.org/10.1080/14756360801969325

Affiliations: 1: School of Studies in Chemistry, Jiwaji University, Gwalior, India

Publication date: 2009-02-01

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