CRACking ion channel targets: 2nd Annual Ion Channel Targets Conference
Author: Mathes, Chris
Source: Expert Opinion on Therapeutic Targets, Volume 11, Number 1, January 2007 , pp. 101-104(4)
Publisher: Informa Healthcare
Abstract:
The 2nd Annual Ion Channel Targets (ICT) Conference (by Select Bioscience LLC) was held in Boston on 12 - 13 September 2006. A healthy mixture of scientists from pharma, biotech and academic sectors attended the meeting. The speaker list reflected this mixture. In general, the conference focused on new ion channel targets and the methods for studying them in detail. Keynote lectures from Professors David Clapham (Harvard Medical School, USA) and Reinhold Penner (University of Hawaii, USA) set the tone by highlighting recent findings with a voltage-gated proton channel (Clapham), cation channel in sperm (Clapham) and the calcium-release-activated calcium channel (Penner). Also described at ICT were voltage-gated sodium, potassium, transmembrane-receptor-potential channels, as well as ligand-gated nicotinic acetylcholine (nAChR) and GABA type A receptors.Keywords: automated patch clamp; cardiac safety; drug discovery; electrophysiology; high throughput; ion channel; patch clamp
Document Type: Research article
DOI: http://dx.doi.org/10.1517/14728222.11.1.101
Publication date: 2007-01-01
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