Expert Opinion on Therapeutic Targets

A new therapeutic target for atherosclerosis treatment: interview with Uday Saxena
pp. 1-3(3)

Targeting vascular endothelial growth factor in angina therapy
pp. 5-14(10)
Authors: Boodhwani, Munir; Ramlawi, Basel; Laham, Roger J; Sellke, Frank W

Targeting Brn-3b in breast cancer therapy
pp. 15-25(11)
Authors: Budhram-Mahadeo, Vishwanie S; Latchman, David S

The role of cellular flice inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer
pp. 27-35(9)
Authors: Dutton, Amanda; Young, Lawrence S; Murray, Paul G

Targeting chaperones in transformed systems – a focus on Hsp90 and cancer
pp. 37-50(14)
Author: Chiosis, Gabriela

Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML
pp. 51-68(18)
Authors: Bruserud, Øystein; Stapnes, Camilla; Tronstad, Karl Johan; Ryningen, Anita; Ånensen, Nina; Gjertsen, Bjørn Tore

The small-molecule immune response modifier imiquimod – its mode of action and clinical use in the treatment of skin cancer
pp. 69-76(8)
Authors: Schön, Michael P; Schön, Margarete

Targeting Aurora kinases in ovarian cancer
pp. 77-85(9)
Authors: Fu, Siqing; Hu, Wei; Kavanagh, John J; Bast Jr, Robert C

From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer
pp. 87-118(32)
Authors: Aggarwal, Bharat B; Ichikawa, Haruyo; Garodia, Prachi; Weerasinghe, Priya; Sethi, Gautam; Bhatt, Indra D; Pandey, Manoj K; Shishodia, Shishir; Nair, Muraleedharan G

Adipose targets for obesity drug development
pp. 119-134(16)
Authors: Boss, Olivier; Bergenhem, Nils

Shp2 as a therapeutic target for leptin resistance and obesity
pp. 135-142(8)
Author: Feng, Gen-Sheng

Targeting matrix metalloproteases to improve cutaneous wound healing
pp. 143-155(13)
Authors: Xue, Meilang; Le, Nghia TV; Jackson, Christopher J

Targeting the PTPome in human disease
pp. 157-177(21)
Authors: Tautz, Lutz; Pellecchia, Maurizio; Mustelin, Tomas

Transcreener™: screening enzymes involved in covalent regulation
pp. 179-190(12)
Authors: Lowery, Robert G; Kleman-Leyer, Karen

Ceramide as a target in emphysema
pp. 191-194(4)
Author: Doggrell, Sheila A