The promise of cytokine antibody arrays in the drug discovery process

Authors: Huang, Ruo-Pan; Yang, Weimin; Yang, Dongzi; Flowers, Lisa; Horowitz, Ira R; Cao, Xuan; Huang, Ruochun

Source: Expert Opinion on Therapeutic Targets, Volume 9, Number 3, 1 June 2005 , pp. 601-615(15)

Publisher: Informa Healthcare

Key:

- Free Content

- New Content

- Subscribed Content

- Free Trial Content

Abstract:

The introduction of cytokine antibody arrays has added a new approach for investigators to simultaneously measure multiple cytokine levels in biological samples. Several different platforms have been developed. The ability to measure hundreds of cytokine levels with high specificity and sensitivity within a very limited amount of samples is a powerful tool. Many investigators worldwide have applied this novel technology in their biomedical research, particularly in drug discovery. Undoubtedly, the technology will continue to be improved and the application increased in the next several years.

Keywords: antibody array; cytokine; drug discovery; protein array

Document Type: Review article

DOI: 10.1517/14728222.9.3.601

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$99.00 plus tax Refund Policy