Travoprost/timolol fixed combination

Authors: Herceg, Michael; Noecker, Robert

Source: Expert Opinion on Pharmacotherapy, Volume 9, Number 6, April 2008 , pp. 1059-1065(7)

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Abstract:

Background: Travoprost and timolol are topical ocular hypotensive medications that have been used in the treatment of glaucoma. The fixed combination eye drop, Duotrav (travoprost 0.004% and timolol maleate 0.5%), has recently been introduced into the market. Objective: In this paper, the results of clinical trials and existing data on the performance of travoprost/timolol are discussed and analyzed. Methods: Appopriate studies for review were identified using PubMed. Studies selected for review compared efficacy and side-effect profile of fixed combination travoprost/timolol with travoprost and timolol used concomitantly, latanoprost and timolol used concomitantly, fixed combination latanoprost/timolol, travoprost alone and timolol alone. Results/conclusion: Fixed combination eye drops such as travoprost/timolol offer the potential benefits of increased patient adherence, reduced exposure to preservatives, and reduced cost.

Keywords: DuoTrav; eye drop; fixed combination; glaucoma; ocular hypertension; timolol; travatan; travoprost

Document Type: Research article

DOI: http://dx.doi.org/10.1517/14656566.9.6.1059

Affiliations: 1: University of Pittsburgh School of Medicine, UPMC Eye Center, 203 Lothrop Street, Suite 820, Pittsburgh, PA 15213, USA +1 412 647 2152; +1 412 647 5119;

Publication date: 2008-04-01

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