Colloidal carriers for the enhanced delivery through the skin
Authors: Cosco, D; Celia, C; Cilurzo, F; Trapasso, E; Paolino, D
Source: Expert Opinion on Drug Delivery, Volume 5, Number 7, July 2008 , pp. 737-755(19)
Publisher: Informa Healthcare
Abstract:Background: The skin is the largest organ of our body and acts as a protective barrier with sensory and immunological functions. Its peculiar structure influences the passage of bioactives and only its modulation can facilitate the drug dermal/transdermal diffusion. In the past few years research in this field has assured better use of this application area. Methods: One of the most promising approaches is the use of drug delivery devices; this review explains the state of the art of drug transport through the skin by means of vesicular (classic liposomes, Transfersomes, niosomes and ethosomes) and particulate systems. Results/conclusion: Colloidal drug delivery systems are important in the field of drug delivery systems as their different characteristics make them suitable for various purposes.
Document Type: Research Article
Publication date: 2008-07-01