Dose accuracy of a reusable insulin pen using a cartridge system with an integrated plunger mechanism
Source: Expert Opinion on Drug Delivery, Volume 3, Number 5, September 2006 , pp. 677-683(7)
Publisher: Informa Healthcare
Abstract:Pen injection devices are a common method of administering insulin for patients with diabetes. Pen devices must comply with guidelines prepared by the International Organization for Standardization, which include device dose accuracy and precision. OptiClik® (sanofi-aventis) was developed to fulfil unmet needs of patients with diabetes, including: easier cartridge changing, clearer dose display and readability, and a larger dose of insulin to be delivered with a single injection. In this paper, the authors report on the dose accuracy of the OptiClik pen device, which uses a novel cartridge system with an integrated plunger for easier cartridge changing. The authors show that OptiClik accurately delivers a required dose of insulin, which is maintained over the lifetime of the pen. OptiClik offers a significant contribution to the treatment of diabetes.
Document Type: Research Article
Affiliations: 1: 1Head of Device Design & Industrialisaton, sanofi-aventis, Deutschland GmbH, Industriepark Hoechst, Building K607, 65843 Frankfurt am Main, Germany., Email: Alastair.Clarke@sanofi-aventis.com 2: 2Diabetes Medical Director, Global Metabolism, sanofi-aventis, Paris, France
Publication date: September 1, 2006