Authors: Hyrup, Birgitte; Andersen, Carsten; Andreasen, Lars Vibe; Tandrup, Bo; Christensen, Torben

Source: Expert Opinion on Drug Delivery, Volume 2, Number 5, 1 September 2005 , pp. 927-933(7)

Publisher: Informa Healthcare

Abstract:

A few decades ago, chewing gum was rarely considered when industry searched for an applicable delivery vehicle for an active pharmaceutical substance. Yet, the 1980s and 1990s saw gum become the most successful nicotine delivery form; unawareness changed to cautious scepticism, and today the merits of chewing gum drug delivery technologies are generally appreciated. MediChew^® is the registered trademark of Fertin Pharma’s medical chewing gum technology platform. Based on patent-protected technologies, it offers unique taste-masking possibilities and allows control of drug molecule release. Medical chewing gum products based on these technologies are specifically suitable for convenient administration on demand, for active substances providing a topical effect in the oral cavity and throat, and for systemic delivery of drug molecules that readily cross the oromucosal membranes.

Keywords: controlled release; drug delivery; medical chewing gum; medicated chewing gum; MediChew®; modified release

Document Type: Miscellaneous

DOI: http://dx.doi.org/10.1517/17425247.2.5.927

Publication date: 2005-09-01

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