IngentaConnect Exogenous endoscopy-related infections, pseudo-infections, and to...

Authors: Seoane-Vazquez, Enrique¹; Rodriguez-Monguio, Rosa²; Visaria, Jay³; Carlson, Angeline⁴

Source: Current Medical Research and Opinion, Volume 22, Number 10, October 2006 , pp. 2007-2021(15)

Abstract:

Objectives: The objective of this study was to analyze the characteristics and costs of exogenous endoscopy-related infections, pseudo-infections, and toxic reactions in the US.

Methods: A systematic review of the scientific literature published between 1966 and 2005 was conducted in Medline. Data collection was based on a prospective protocol developed by the authors.

Results: The literature review included 70 outbreaks described in 64 scientific articles. Bronchoscopy accounted for half of all reported outbreaks. Inadequate decontamination practices were the leading cause of contamination; equipment malfunction became the second leading cause of contamination during the period 1990-2004. More than 91% of the infections identified could be prevented by health care providers if quality control systems are improved and implemented. The available economic information concerning exogenous endoscope related events is very limited. A model for the analysis of the economic burden of exogenous endoscopy-related events is proposed.

Conclusions: Proper decontamination practices, the use of protective sheaths, and the improvement of surveillance systems could reduce the clinical and economic burdens associated with exogenous endoscopy-related events.

Keywords: COST ANALYSIS; ENDOSCOPY; HAZARDOUS CHEMICALS; MEDICAL DEVICES; NOSOCOMIAL INFECTIONS

Document Type: Review article

DOI: 10.1185/030079906X121048

Affiliations: 1: College of Pharmacy, The Ohio State University, Columbus, Ohio, USA; School of Public Health, The Ohio State University, Columbus, Ohio, USA; Center for Health Outcomes, Policy and Evaluation Studies, The Ohio State University, Columbus, Ohio, US 2: School of Public Health, The Ohio State University, Columbus, Ohio, USA; Center for Health Outcomes, Policy and Evaluation Studies, The Ohio State University, Columbus, Ohio, USA 3: College of Pharmacy, The Ohio State University, Columbus, Ohio, USA 4: Data Intelligence Consultants, LLC, and College of Pharmacy, University of Minnesota, Minneapolis, USA

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Exogenous endoscopy-related infections, pseudo-infections, and toxic reactions: clinical and economic burden