Predictors of high-cost managed care patients with acute coronary syndrome

Authors: Etemad, Lida R.1; McCollam, Patrick L.2

Source: Current Medical Research and Opinion, Volume 21, Number 12, December 2005 , pp. 1977-1984(8)

Publisher: Informa Healthcare

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Abstract:

Objective: To develop predictive models of high-cost acute coronary syndrome (ACS) patients using demographic, disease, and treatment characteristics.

Study design: This was a retrospective, administrative claims analysis utilizing pharmacy, medical, and eligibility data from a large US managed care organization.

Methods: ACS was defined by ICD-9 codes for unstable angina (UA) or acute myocardial infarction (AMI). New onset patients (without ACS claims) in the prior six months were identified for the time period 07/01/99–06/30/01, and followed up to 12 months, health plan disenrollment, or death. Cost was measured as that incurred during the initial episode plus subsequent follow-up or during the subsequent follow-up only. Patients were dichotomized as high-cost (top 20%) or low-cost (bottom 80%), based on total costs. Logistic regression was used to examine the association for being classified as high-cost.

Results: A total of 13 731 patients were included: 51.7% with UA, 39.6% with AMI and 8.7% with both UA and AMI. The mean age was 54.2 years and 68.2% were male. A number of co-morbidities (hypertension, diabetes, heart failure, etc.) predicted high-cost patients. Among medications, prior ACE inhibitor use predicted high-cost patients. While revascularization procedures, in general, were strong predictors of high-cost, revascularization during the index ACS episode (opposed to revascularization during the follow-up) decreased the odds of being high-cost (odds ratio [95% CI] 0.615 [0.506–0.748]).

Conclusion: High-cost patients with new onset ACS can be predicted by some characteristics, but many of these characteristics are non-modifiable co-morbidities. Payers and providers may find opportunities for clinical and cost-saving interventions for these patients.

Keywords: ANGINA, UNSTABLE; HEALTH EXPENDITURES; HEALTH MAINTENANCE ORGANIZATION; MYOCARDIAL INFARCTION

Document Type: Research article

DOI: 10.1185/030079905X74970

Affiliations: 1: i3 Magnifi, an Ingenix Company, 12125 Technology Dr., Eden Prairie, MN 55344, USA 2: Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA

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