Emerging guidelines for use of NSAID therapy to optimize cataract surgery patient care

Author: O'Brien, T.P.

Source: Current Medical Research and Opinion, Volume 21, Number 7, July 2005 , pp. 1131-1138(8)

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Abstract:

This analysis provides guidelines for the proper use of topical ophthalmic nonsteroidal anti-inflammatory drugs (NSAIDs), discusses their effect on inflammation, and their role in the prevention of cystoid macular edema (CME). A novel treatment strategy is presented for recommended topical ophthalmic NSAID dosing in patient populations based on risk factors for CME. The article reviews current topical ophthalmic NSAIDs, as well as a newest generation of pro-drug NSAIDs. In addition, combination therapy of NSAIDs and corticosteroids are discussed, along with a general review of therapeutic guidelines for dosing regimens, and benefits and risks of therapy. The goal of this analysis is to provide a suggested therapeutic regimen with topical NSAIDs to assist in achieving optimal clinical and functional outcomes.

Keywords: CATARACT TREATMENT STRATEGY; CYSTOID MACULAR EDEMA; NONSTEROIDAL ANTI-INFLAMMATORY DRUGS

Document Type: Commentary

DOI: http://dx.doi.org/10.1185/030079905X50651

Affiliations: 1: The Wilmer Ophthalmology Institute, The Johns Hopkins Hospital, Baltimore, MD, USA

Publication date: 2005-07-01

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