Lateral frontal cortical contribution to memory

Author: Petrides M.

Source: Seminars in Neuroscience, Volume 8, Number 1, 1996 , pp. 57-63(7)

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Abstract:

Recent studies of the mnemonic effects of selective lesions within the lateral frontal cortex in the monkey have suggested that the mid-dorsolateral region may be a specialized system for the monitoring and manipulation of information within working memory. This impairment appears against a background of normal performance on several basic mnemonic tasks. By contrast, a more severe impairment follows damage to the mid-ventrolateral frontal region. Functional activation studies with normal human subjects have confirmed the suggestion from the animal work that the mid-dorsolateral region is involved in the monitoring and manipulation of information within working memory.

Keywords: memory; monkey; patients

Language: English

Document Type: Miscellaneous

Affiliations: Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada

Publication date: 1996-01-01