Genetic predisposition to cancer-issues to consider

Authors: Malkin D.¹; Knoppers B.M.²

Source: Seminars in Cancer Biology, Volume 7, Number 1, 1996 , pp. 49-53(5)

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Abstract:

The importance of molecular genetic events in the development of inherited cancers has evolved from the clinical study, molecular and genetic epidemiology and molecular biology of affected families. As our understanding of the mechanisms of carcinogenesis improves, numerous concerns revolving around the potential impact of laboratory-based predictive genetic testing arise. Through multi-disciplinary approaches supported in part by the Human Genome Project and other research efforts, information is being gathered that may lay the foundation for legislative, scientific and clinical guidelines and recommendations throughout the international community.

Keywords: diagnosis; prognosis

Language: English

Document Type: Miscellaneous

Affiliations: 1: Division of Oncology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Canada 2: Faculty of Law and Centre for Public Law Research, University of Montreal, Canada

Publication date: 1996-01-01