Distribution of Thromboxane A 2 Receptor mRNA along the Mouse Nephron Segments
Authors: Asano, K.; Taniguchi, S.; Nakao, A.; Maruyama, T.; Watanabe, T.; Kurokawa, K.
Source: Biochemical and Biophysical Research Communications, Volume 226, Number 3, September 1996 , pp. 613-617(5)
Publisher: Academic Press
Abstract:Thromboxane A 2 (TXA 2 ) receptor mRNA was semi-quantitated in microdissected mouse nephron segments by reverse transcription-polymerase chain reaction (RT-PCR). TXA 2 receptor mRNA was most abundantly expressed in the glomerulus, followed by the distal convoluted tubule > proximal tubule, thick ascending limb of Henle, and outer medullary collecting duct. These results suggest the potential physiological roles of TXA 2 in the entire renal tubule as well as in the glomerulus.
Document Type: Research Article
Affiliations: Faculty of Medicine, The University of Tokyo, Tokyo, 113, Japan
Publication date: 1996-09-01