Twenty heifers which were each administered 3 or 4 implants containing trenbolone acetate were slaughtered at 30 days post-implantation. Liquid chromatographic analyses were conducted on muscle collected from the rump, loin, shoulder, and neck, and on the liver of each animal. Residues
present in liver were primarily 17-trenbolone, and the residues found in the various muscle samples were primarily 17-trenbolone. The mean concentration of 17-trenbolone in liver was 4.3 2.3 ng/g; the mean concentration of 17-trenbolone in muscle tissues was <0.4 ng/g. There was a small
but statistically significant effect of the number of implants used on the mean concentration of residues in loin muscles; animals with 3 trenbolone implants had higher mean residue concentrations than animals with 4 trenbolone implants. This suggests that, though the impact of implant numbers
on the mean concentration of residues in muscle tissues is negligible relative to currently generally accepted maximum residue levels, mechanisms may exist for selective distribution and retention of residues within different muscle groups.
Document Type: Research Article
Canadian Food Inspection Agency, Center for Veterinary Drug Residues, Saskatoon Laboratory, 116 Veterinary Rd, Saskatoon, SK, Canada S7N 2R3.
Publication date: May 1, 2008
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