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Policy on Characterization of Antibodies Used in Immunochemical Methods of Analysis for Mycotoxins and Phycotoxins

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The purpose of this document is to provide a policy on antibody characterization for conducting AOAC collaborative studies for immunochemical methods submitted for AOAC® Official Methods SM Program status. The policy defines recommended information and characteristics to be provided by the Study Director, in the protocol of the collaborative study, for approval by AOAC. The document specifies parameters for characterization of antibodies used as biological reagent in the protocol of validation of immunochemical methods for the determination of mycotoxins and phycotoxins. These recommendations are applicable to the validation of any method, whether proprietary or non-proprietary, that is submitted to AOAC for Official Methods of Analysis SM status recognition.
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Document Type: Research Article

Affiliations: 1: French Agency for Food Safety, Food Hygiene and Quality Laboratory, 10 r. P. Curie, F94704 Maisons Alfort, France 2: Dairy Science, Institute of Veterinary Food Science, Justus-Liebig-University, Ludwigstrasse 21, 35390 Giessen, Germany

Publication date: 01 July 2003

More about this publication?
  • The Journal of AOAC INTERNATIONAL publishes refereed papers and reviews in the fields of chemical, biological and toxicological analytical chemistry for the purpose of showcasing the most precise, accurate and sensitive methods for analysis of foods, food additives, supplements and contaminants, cosmetics, drugs, toxins, hazardous substances, pesticides, feeds, fertilizers and the environment available at that point in time. The scope of the Journal includes unpublished original research describing new analytical methods, techniques and applications; improved approaches to sampling, both in the field and the laboratory; better methods of preparing samples for analysis; collaborative studies substantiating the performance of a given method; statistical techniques for evaluating data. The Journal will also publish other articles of general interest to its audience, e.g., technical communications; cautionary notes; comments on techniques, apparatus, and reagents.
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