Skip to main content

Determination of Ciprofloxacin with a Room-Temperature Phosphorescence Flow-Through Sensor Based on Lanthanide-Sensitized Luminescence

Buy Article:

$50.00 plus tax (Refund Policy)


Direct measurement of the sensitized luminescence of the europium-ciprofloxacin chelate immobilized on a cationic exchanger was used to develop a flow-through room-temperature phosphorescence optosensor for determination of ciprofloxacin. The phosphorescent chelate is formed on-line at room temperature in a flow-injection system and is immobilized on a weakly acidic cation-exchange resin packed in a flow cell. Optimum experimental conditions and analytical performance are discussed in detail. The sensor response for ciprofloxacin was linear, from 1.5 × 10−6 to 2.0 × 10−5M with a relative standard deviation of 2.5% (n = 10) and a detection limit of 1.1 × 10−7M. The effect of possible interferences on sensor response was studied. The sensor was successfully tested for the determination of ciprofloxacin in pharmaceutical formulations.

Document Type: Research Article

Affiliations: University of Jaén, Department of Physical and Analytical Chemistry, E-23071 Jaén, Spain.

Publication date: 2002-11-01

More about this publication?
  • The Journal of AOAC INTERNATIONAL publishes refereed papers and reviews in the fields of chemical, biological and toxicological analytical chemistry for the purpose of showcasing the most precise, accurate and sensitive methods for analysis of foods, food additives, supplements and contaminants, cosmetics, drugs, toxins, hazardous substances, pesticides, feeds, fertilizers and the environment available at that point in time. The scope of the Journal includes unpublished original research describing new analytical methods, techniques and applications; improved approaches to sampling, both in the field and the laboratory; better methods of preparing samples for analysis; collaborative studies substantiating the performance of a given method; statistical techniques for evaluating data. The Journal will also publish other articles of general interest to its audience, e.g., technical communications; cautionary notes; comments on techniques, apparatus, and reagents.
  • Information for Authors
  • Submit a Paper
  • Subscribe to this Title
  • Information for Advertisers
  • Journal Information
  • Masthead
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more