Authors: Gariti, Katherine O.¹; Sadeghi, Leila²; Joisa, Sowmya D.³; Holmes, William C.⁴

Source: Military Medicine, Volume 174, Number 11, November 2009 , pp. 1149-1154(6)

Publisher: AMSUS - Association of Military Surgeons of the U.S.

Abstract:

ABSTRACT

Unintended consequences of participating in research studies are not well characterized, particularly in veterans who are frequent study participants. Our objective, then, was to assess the rate of and variables associated with distress resulting from veterans' participation in a study on a sensitive subject. Veterans Administration (VA) hospital outpatients were administered questionnaires with three increasingly severe scenarios of a U.S. soldier abusing a detainee. Distress—upset requiring clinical intervention—was assessed, as were sociodemographic characteristics, post-traumatic stress disorder (PTSD), depression, and locus of control (LOC). Three hundred fifty-one veterans participated. Forty-three (12%) became distressed. Modeling indicated distress was associated with minority status (odds ratio [OR] = 5.72, 95% confidence interval [CI] = 1.59, 20.58), PTSD (OR = 2.66, 95% CI = 1.12, 6.29), and external LOC (OR = 6.27, 95% CI = 2.82, 13.90). Distress related to study participation was high in this veteran sample. Higher rates in some subgroups suggested that some individuals may not be able to accurately anticipate risk for harm in sensitive studies.

Document Type: Research article

Affiliations: 1: Mental Health Clinic, Philadelphia Veterans Affairs Medical Center, University and Woodland Avenues, Philadelphia, PA 19104. 2: NYU Langone Medical Center, Department of Pediatrics, 550 First Avenue, New York, NY 10016. 3: The Good Samaritan Hospital, 4th and Walnut Streets, Lebanon, PA 17042. 4: Center for Health Equity Research and Promotion, Philadelphia Veterans Affairs Medical Center, University and Woodland Avenues, Philadelphia, PA 19104.

Publication date: 2009-11-01

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• Military Medicine is the Association's official monthly journal. The objective of the Journal is to promote awareness of Federal medicine by providing a forum for responsible discussion of common ideas and problems relevant to Federal healthcare. Its mission is: To increase healthcare education by providing scientific and other information to its readers; to facilitate communication; and to offer a prestige publication for members' writings.
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