Immunization against Haemophilus influenzae Type B Fails to Prevent Orbital and Facial Cellulitis - Results of a 25-Year Study among Military Children
Authors: Cieslak, Theodore J.; Rajnik, Michael; Roscelli, John D.
Source: Military Medicine, Volume 173, Number 10, October 2008 , pp. 941-944(4)
Abstract:Vaccines against Haemophilus influenzae type B (HI) and Streptococcus pneumoniae (SP) have dramatically reduced the incidence of bacterial meningitis (due to both HI and SP) and epiglottitis (due to HI) in childhood. The effects of these vaccines on other conditions, however, are less clear. We report an analysis of the effect of serial deployment of various HI and SP vaccines over a 25-year period, involving an examination of over half a million pediatric hospitalizations occurring in Army hospitals worldwide. We show that, in marked contrast to the reduction in the number of meningitis and epiglottitis cases, the disease burden of orbital and facial cellulitis—conditions oft attributed to HI and SP—did not diminish.
Document Type: Research Article
Affiliations: San Antonio Military Pediatric Center, c/o Wilford Hall Medical Center, San Antonio, TX 78236.
Publication date: October 2008
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Military Medicine is the Association's official monthly journal. The objective of the Journal is to promote awareness of Federal medicine by providing a forum for responsible discussion of common ideas and problems relevant to Federal healthcare. Its mission is: To increase healthcare education by providing scientific and other information to its readers; to facilitate communication; and to offer a prestige publication for members' writings.
Military Medicine's 5-year Impact Factor: 1.061
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