@article {Buff:2008:0026-4075:588, author = "Buff, Ann M. and Deshpande, Swati J. and Harrington, Theresa A. and Wofford, Taylor S. and O'Hara, Timothy W. and Carrigan, Kenichi and Martin, Nicholas J. and McDowell, Jackie C. and Ijaz, Kashef and Jensen, Paul A. and Lambert, Lauren A. and Moore, Marisa and Oeltmann, John E.", title = "Investigation of Mycobacterium tuberculosis Transmission Aboard the U.S.S. Ronald Reagan, 2006", journal = "Military Medicine", volume = "173", number = "6", year = "2008", abstract = "Pulmonary tuberculosis (TB) was diagnosed in a sailor aboard the U.S.S. Ronald Reagan; an investigation was conducted to determine a screening strategy for 1,172 civilian passengers who were aboard during a temporary guest rider program. Sailors were screened for latent TB infection (LTBI) and TB disease. A case-control study was conducted among sailors to determine factors associated with new LTBI. No secondary TB disease was identified; 13% of close contacts had new LTBI. Factors associated with new LTBI among sailors were having been born outside the United States (adjusted odds ratio = 2.80; 95% confidence interval, 1.55-5.07) and being a carrier air wing member (adjusted odds ratio = 2.89; 95% confidence interval, 1.83-4.58). Among 38 civilian passengers berthed near the patient, 1 (3%) had LTBI. The investigation results indicated that Mycobacterium tuberculosis transmission was minimal and eliminated unnecessary TB screening for 1,134 civilians which saved public health resources.", pages = "588-593", url = "http://www.ingentaconnect.com/content/amsus/zmm/2008/00000173/00000006/art00031" }