Reactions Weekly

Statins found to adversely affect energy, cause fatigue on exertion
pp. 1-1(1)

Singapore the global leader in number of AE reports in 2006-2011
pp. 2-2(1)

Japan's PMDA warns of serious AEs with pivoxil use in kids
pp. 2-2(1)

BCG vaccine recalled by Sanofi Pasteur in Canada
pp. 2-2(1)

NZ Medsafe receives reports of RCVS linked to serotonergic drugs
pp. 3-3(1)

Infants at risk with OTC use of benzocaine, says FDA
pp. 3-3(1)

Over 60 reports of serious pulmonary reactions following the use of nitrofurantoin have been received
pp. 3-3(1)

No major safety concerns with compounded hydroxyprogesterone
pp. 3-3(1)

Statin + ciclosporin interaction highlighted by NZ Medsafe
pp. 4-4(1)

Psych drugs in drinking water may be linked to autism
pp. 4-4(1)

Drug-resistant TB a "serious epidemic" in China
pp. 4-4(1)

New Zealand's Medsafe is to launch the suspected medicine adverse reaction search (SMARS) database
pp. 4-4(1)

Aciclovir: Bullous cutaneous eruption due to extravasation: case report
pp. 5-5(1)

Adalimumab: Alopecia areata: case report
pp. 5-5(1)

Aciclovir/ampicillin/ceftriaxone/doxycycline: Jarisch-Herxheimer reaction (first report for aciclovir): case report
pp. 5-5(1)

Adalimumab: Systemic lupus erythematosus: case report
pp. 5-6(2)

Allopurinol: Delayed allergic reactions and fixed drug eruption managed with desensitisation: case report
pp. 6-6(1)

Adalimumab: Urinary tuberculosis: case report
pp. 6-6(1)

Allopurinol: Immune thrombocytopenic purpura in an elderly patient: case report
pp. 6-6(1)

Alcohol: Iatrogenic femoral nerve injury: case report
pp. 6-6(1)

Aminolevulinic acid: Skin crusting following intradermal injection: case report
pp. 7-7(1)

Allopurinol/levofloxacin: Ocular mucous membrane pemphigoid (first report for levofloxacin) following Lyell syndrome: 2 case reports
pp. 7-7(1)

Amantadine: Livedo reticularis: case report
pp. 7-7(1)

Amiodarone: Peripheral neuropathy: case report
pp. 7-8(2)

Amiodarone: Volkmann's-like syndrome (first report) following extravasation: case report
pp. 8-8(1)

Amiodarone: Toxic epidermal necrolysis in an elderly patient: case report
pp. 8-8(1)

Amoxicillin/clavulanic acid/tacrolimus interaction: Cholestatic liver injury in a child?: case report
pp. 8-8(1)

Anabolic steroids abuse: Congestive heart failure and eosinophilic myocarditis: 2 case reports
pp. 8-9(2)

Antiasthmatics: Lactic acidosis: case report
pp. 9-9(1)

Antineoplastics: Gastric perforation in an elderly patient: case report
pp. 9-9(1)

Antineoplastics: Various toxicities: 3 case reports
pp. 10-10(1)

Antineoplastics: Neutropenia and nausea: 5 case reports
pp. 10-10(1)

Antineoplastics: Neutropenia: case report
pp. 10-10(1)

Antineoplastics/hydrocortisone: Various toxicities in a child: case report
pp. 10-11(2)

Antineoplastics: Leukoencephalopathy in an elderly patient?: case report
pp. 10-11(2)

Antineoplastics/immunosuppressants: Encephalopathy in paediatric patients: 5 case reports
pp. 11-11(1)

Antipsychotics: Neuroleptic malignant syndrome: case report
pp. 11-11(1)

Artemether/lumefantrine: Haemolytic anaemia: case report
pp. 11-12(2)

Atomoxetine/fluoxetine interaction: Orthostatic hypotension, syncope and tachycardia: case report
pp. 12-12(1)

Asparaginase: Pancreatitis in children: 3 case reports
pp. 12-12(1)

Atorvastatin: Drug-induced lupus erythematosus: case report
pp. 12-12(1)

Azathioprine/corticosteroids/infliximab: Triple fungal infection: case report
pp. 12-13(2)

BCG: Bilateral orbital inflammation following intravesical administration: case report
pp. 13-13(1)

Bee venom allergy immunotherapy/wasp venom allergy immunotherapy: Hypersensitivity reactions in paediatric patients: 16 case reports
pp. 13-13(1)

Benzylpenicillin: Jarisch-Herxheimer reaction causing strokes: case report
pp. 13-14(2)

Bleomycin: Vasculopathy following intracystic administration in a child: case report
pp. 14-14(1)

Betamethasone/methylprednisolone: Steroid psychosis in an elderly patient, treated with risperidone: case report
pp. 14-14(1)

Bevacizumab: Bowel perforation after stent placement in an elderly patient: case report
pp. 14-14(1)

Bortezomib: Congestive heart failure: case report
pp. 14-14(1)

Carbimazole/iodine-131: Hypersensitivity reactions and hypocalcaemia due to hypoparathyroidism: case report
pp. 15-15(1)

Carbamazepine/quetiapine interaction: Mixed poisoning leading to cardiotoxicity: case report
pp. 15-15(1)

Carvedilol/dronedarone interaction: Bradycardia, syncope and prolonged QTc interval: case report
pp. 15-15(1)

Cephalosporins/piperacillin: Delayed hypersensitivity and anaphylactic shock: 8 case reports
pp. 16-16(1)

Chlorpromazine/haloperidol/promethazine: Neuroleptic malignant syndrome: case report
pp. 16-16(1)

Celecoxib: Hepatorenal syndrome in an elderly patient: case report
pp. 16-16(1)

Ciclosporin: Nephrotoxicity and hyperlipidaemia: 3 case reports
pp. 16-17(2)

Ciclosporin: Tremor and posterior reversible encephalopathy syndrome: case report
pp. 17-17(1)

Citalopram/fluvoxamine interaction: Galactorrhoea: case report
pp. 17-17(1)

Clarithromycin/ibuprofen/paracetamol: Erythroderma: case report
pp. 17-18(2)

Clozapine: First report of palilalia: case report
pp. 18-18(1)

Clindamycin: Clostridium difficile infection: case report
pp. 18-18(1)

Clobazam/oxcarbazepine/zonisamide: First report of secondary hyperparathyroidism, brown tumour and fracture of neck of femur: case report
pp. 18-18(1)

Clozapine/propranolol: Tachycardia, psoriasis and metabolic syndrome: case report
pp. 18-19(2)

Colecalciferol overdose: Severe hypercalcaemia in an infant: case report
pp. 19-19(1)

Colchicine/pristinamycin interaction: Fatal multivisceral failure and shock, following colchicine overdose, in an elderly patient: case report
pp. 19-19(1)

Cytarabine: Febrile neutropenia and Klebsiella pneumoniae bacteraemia in an elderly patient: case report
pp. 19-20(2)

Cytarabine/methotrexate: Transient leukoencephalopathy: case report
pp. 20-20(1)

Diclofenac: Acute localised pustulosis to sodium metabisulphite excipient: case report
pp. 20-20(1)

Cytisine/mianserin/moclobemide/venlafaxine overdose: Serotonin syndrome: case report
pp. 20-20(1)

Dabigatran etexilate: Nosebleed in an elderly patient: case report
pp. 20-20(1)

Doxorubicin liposomal: Erythema, swelling and desquamation following extravasation: case report
pp. 21-21(1)

Digoxin overdose: Gastrointestinal, neurological and cardiovascular symptoms: case report
pp. 21-21(1)

Diclofenac: Autoimmune haemolytic anaemia in an elderly patient: case report
pp. 21-21(1)

Docetaxel: Diarrhoea: case report
pp. 21-21(1)

Doxorubicin lipsomal: Palmar-plantar erythrodysaesthesia in an elderly patient: case report
pp. 22-22(1)

Doxycycline: Jarisch-Herxheimer reaction in a child: case report
pp. 22-22(1)

Doxycycline: Oesophageal ulcers: case report
pp. 22-22(1)

Emtricitabine/nevirapine/tenofovir: Acute liver failure: case report
pp. 22-23(2)

Escitalopram: Subclinical hypothyrodism: case report
pp. 23-23(1)

Eprosartan/hydrochlorothiazide: Lichenoid drug eruption in an elderly patient: case report
pp. 23-23(1)

Ergotamine: Acute coronary syndrome: case report
pp. 23-23(1)

Epinephrine: Coronary vasospasm in a patient undergoing cardiopulmonary resuscitation: case report
pp. 23-23(1)

Fampridine: Various toxicities: 6 case reports
pp. 24-24(1)

Etanercept: Palmoplantar pustulosis: case report
pp. 24-24(1)

Fluoxetine: Noctural bruxism: case report
pp. 24-24(1)

Fentanyl abuse: Development of dependence: 2 case reports
pp. 24-24(1)

Fosfomycin/polymixin B: Lack of efficacy of fosfomycin and development of resistance to polymixin B in a Klebsiella pneumoniae infection: case report
pp. 25-25(1)

Fucus vesiculosus/lithium interaction: Hyperthyroidism: case report
pp. 25-25(1)

Fotemustine: Diffuse interstitial lung disease (first report) in an elderly patient: case report
pp. 25-25(1)

Furosemide: Severe dehydration and persistent chronic renal failure in an infant: case report
pp. 25-25(1)

Gabapentin abuse/overdose: First report of posterior reversible leukoencephalopathy syndrome: case report
pp. 26-26(1)

Hydrogen peroxide: Gas orbitopathy due to orbital emphysema: case report
pp. 26-26(1)

Gemcitabine: Haemolytic uraemic syndrome manifesting as livedo reticularis: case report
pp. 26-26(1)

Ibuprofen: Cholestatic hepatitis: case report
pp. 27-27(1)

Imatinib: Development of imatinib resistance in EGISTs: case report
pp. 27-27(1)

Infliximab: Chilblain lupus in an elderly patient: case report
pp. 27-27(1)

Hydrogen peroxide: Severe chemical colitis following rectal administration: case report
pp. 27-27(1)

Insulin: Lower extremity oedema: case report
pp. 28-28(1)

Ketamine: High blood pressure: case report
pp. 28-28(1)

Ipratropium bromide: Transient anisocoria following inappropriate administration in an infant: case report
pp. 28-28(1)

Isoniazid/phenytoin: Various toxicities: case report
pp. 28-28(1)

Lithium: Hyperparathyroidism: 3 case reports
pp. 29-29(1)

Levodopa: Peak-dose choreoathetotic ankle dyskinesia in patients with Parkin gene mutations: 2 case reports
pp. 29-29(1)

Loxoprofen: Small bowel ulcer: case report
pp. 29-29(1)

Megestrol: Hypogonadism: 2 case reports
pp. 29-30(2)

Methylprednisolone: Diverticular perforation: case report
pp. 30-30(1)

Metformin: Hypomagnesaemia in an elderly patient: case report
pp. 30-30(1)

Mepivacaine: Lingual nerve injury: case report
pp. 30-30(1)

Methotrexate: Severe erythema multiforme delayed-type hypersensitivity: case report
pp. 30-30(1)

Monosodium phosphate/disodium phosphate: Acute renal failure following enema administration: 11 case reports
pp. 31-31(1)

Naproxen/prednisone: Symptomatic hyporeninaemic hypoaldosteronism and Cushing's syndrome in an elderly patient: case report
pp. 31-31(1)

Metoclopramide: First report of postpartum depression: case report
pp. 31-31(1)

Natalizumab/CMX 001: Progressive multifocal leukoencephalopathy and various other toxicities: case report
pp. 31-32(2)

Ornidazole: Intra-oral fixed drug eruption: case report
pp. 32-32(1)

Omeprazole: Depression with psychotic features in an elderly patient: case report
pp. 32-32(1)

Nilotinib/omacetaxine mepesuccinate: Haematotoxicity and cytopenia in an elderly patient: case report
pp. 32-32(1)

Oxcarbazepine/topiramate: Multiple fetal anomalies following in utero exposure: case report
pp. 32-33(2)

Paracetamol: Stevens-Johnson syndrome followed by severe obliterative bronchitis: case report
pp. 33-33(1)

Oxymetazoline: Aortic aneurysm rupture causing death: case report
pp. 33-33(1)

Pegaspargase: Intracranial thrombosis, subsequent haemorrhage, and deep vein thrombosis: case report
pp. 33-34(2)

Perindopril: Visceral angioedema: case report
pp. 34-34(1)

Peginterferon-α-2b/ribavirin: Tongue hyperpigmentation: case report
pp. 34-34(1)

Phenytoin/valproic acid: Gingival enlargement: case report
pp. 34-34(1)

Quetiapine: Dysphagia: case report
pp. 35-35(1)

Somatropin: Multiple osteochondritis dissecans lesions: case report
pp. 35-35(1)

Sulphan blue: Anaphylaxis in an elderly patient: case report
pp. 35-36(2)

Sulpiride overdose: Consciousness disturbances, cardiovascular disorders and miosis: case report
pp. 36-36(1)

Tacrolimus: BK virus nephropathy treated with leflunomide in a child: case report
pp. 36-36(1)

Tegafur: Acral hyperpigmentation: case report
pp. 36-36(1)

Theophylline overdose: Persisent nausea and vomiting in an adolescent: case report
pp. 37-37(1)

Theophylline overdose: Rhabdomyolysis, disseminated intravascular coagulopathy and other toxicities: case report
pp. 37-37(1)

Thioctic acid: Generalised seizures and unconsciousness in an infant: case report
pp. 37-37(1)

Ticlopidine: Isolated systolic hypertension in an elderly patient: case report
pp. 37-38(2)

Tizanidine: Bradycardia and visual hallucinations: case report
pp. 38-38(1)

Topiramate: Acute angle closure glaucoma and progressive myopia: case report
pp. 38-38(1)

Traditional Chinese medicines: Various toxicities due to adulteration of herbal antidiabetic products: 17 case reports
pp. 38-39(2)

Trastuzumab: Cardiotoxicity: 26 case reports
pp. 39-39(1)

Tramadol: Ileus: case report
pp. 39-39(1)

Vandetanib: First report of diffuse interstitial lung disease: case report
pp. 39-39(1)

Vigabatrin: Retinal dystrophy in a child: case report
pp. 40-40(1)

Vigabatrin: Magnetic resonance imaging and spectroscopy abnormalities in infants: 2 case reports
pp. 40-40(1)

Varicella zoster virus vaccine: Varicella zoster virus infection in a neonate following maternal transmission: case report
pp. 40-40(1)

Vincristine: Severe peripheral neuropathy in a child with Charcot-Marie-Tooth disease: case report
pp. 40-41(2)

Vitamin D analogues: Hypercalcaemia and hypervitaminosis D in paediatric patients: 4 case reports
pp. 41-41(1)

Warfarin: Delirium in an elderly patient: case report
pp. 41-41(1)

Warfarin: Iliopsoas haematoma: 2 case reports
pp. 41-42(2)

Zoledronic acid: Fever: 2 case reports
pp. 42-42(1)

Zoledronic acid: Bisphosphonate-related osteonecrosis of the jaw, treated with chlorine dioxide mouthwash: case report
pp. 42-42(1)