Inpharma

Magnesium sulfate needs adding to essential drugs list, say experts
pp. 1-1(1)

Reviving serendipity in drug discovery a "utopian fantasy"?
pp. 2-2(1)

The Centers for Disease Control and Prevention (CDC) should recommend annual influenza vaccinations in children from 6 months up to 18 years
pp. 2-2(1)

Infliximab and adalimumab come out on top for psoriasis
pp. 3-3(1)

Counting the costs for stroke: News from ICS
pp. 3-3(1)

Alendronic acid/colecalciferol more than breaks even
pp. 4-4(1)

One-dose and two-dose US varicella vax strategies worth it?
pp. 4-4(1)

Adding MF59 adjuvant to a subvirion H5N1 influenza A virus vaccine appears to increase immunogenicity
pp. 5-5(1)

A Microcyn Technology platform, containing chlorine dioxide, may be effective for mildly infected diabetic foot ulcers.
pp. 5-5(1)

Everolimus highly active in advanced kidney cancer
pp. 5-5(1)

IV immune globulin (IVIG) therapy was associated with a reduced risk of Alzheimer's disease and related disorders
pp. 5-5(1)

A genetic variation in the Ciliary Neurotrophic Factor (CNTF) gene may alter response to antipsychotic treatment.
pp. 5-5(1)

ARRY 797 arrests pain after tooth extraction
pp. 5-5(1)

Intranasal insulin improves cognitive function in patients with early Alzheimer's disease
pp. 6-6(1)

An RNAi therapeutic, ALN RSV01, showed efficacy against human respiratory syncytial virus (RSV) infection in "a first for the industry"
pp. 6-6(1)

Avotermin [Juvista] may have potential for scar improvement after surgery
pp. 6-6(1)

Toremifene may effectively reduce hot flushes among men undergoing androgen deprivation therapy (ADT) for prostate cancer.
pp. 6-6(1)

Survival in end-stage, treatment-refractory colorectal cancer (CRC) was improved with a glactin-3-targeted therapeutic polysaccharide polymer
pp. 6-6(1)

Certolizumab pegol a sure contender for Crohn's disease
pp. 6-6(1)

Belotecan, a new camptothecin analogue, was found to be "active and promising" in SCLC patients
pp. 7-7(1)

HGS 004 is "safe" and demonstrates "meaningful anti-HIV-1 activity"
pp. 7-7(1)

Gabapentin enacarbil showed benefits in patients with moderate to severe restless legs syndrome
pp. 7-7(1)

A study of a once-daily formulation of tacrolimus [LCP-Tacro] has demonstrated positive results, compared with twice-daily tacrolimus [Prograf]
pp. 7-7(1)

Linaclotide brings relief in chronic constipation, IBS with constipation
pp. 7-7(1)

A meta-analysis showed that use of an antimicrobial lock solution (ALS) decreases the incidence of catheter-related infection
pp. 8-8(1)

Aromatase inhibitors worth a look for ovulation induction in PCOS
pp. 8-8(1)

Antenatal corticosteroids advantageous in preterm infants
pp. 8-8(1)

Weight loss results from the TIPO-2 clinical metabolic study of tesofensine support the positive findings demonstrated in TIPO-1,
pp. 8-8(1)

Inhaled loxapine may be an effective treatment option for patients with migraine
pp. 8-8(1)

Ezetimibe/simvastatin lowers LDL-cholesterol to target levels
pp. 9-9(1)

Gemcitabine in combination with rituximab is effective for the treatment of Hodgkin's disease.
pp. 9-9(1)

Controlled-release (CR) oxycodone is an effective treatment option for patients with chronic neck pain who failed non-opioid treatment
pp. 9-9(1)

Oral sucrose is an effective analgesic for use during routine immunisation among infants.
pp. 9-9(1)

Ganciclovir/valganciclovir beneficial after lung transplant
pp. 9-9(1)

Aripiprazole appears to be an effective option for older adults with bipolar I disorders
pp. 9-9(1)

Nifekalant boosts the efficacy of electrical defibrillation in patients with persistent and paroxysmal atrial fibrillation
pp. 10-10(1)

Substantial mortality reductions when home is where the HAART is
pp. 10-10(1)

Methylphenidate appears to be beneficial for sleep parameters in adults with attention deficit hyperactivity disorder
pp. 10-10(1)

Early oseltamivir treatment enhances survival in avian flu
pp. 10-10(1)

Gemcitabine of no benefit after pancreatic cancer resection
pp. 11-11(1)

Indometacin is effective for the prevention of serious pulmonary haemorrhage in extremely low-birth-weight infants during the first week of life
pp. 11-11(1)

Chemo combos comparable for activity in advanced NSCLC
pp. 11-11(1)

Longer Q-TWiST in early breast cancer with dose-intensive therapy
pp. 11-11(1)

Insulin aspart plus insulin protamine aspart [biphasic insulin aspart 30] may improve glycaemic control in patients with type 2 diabetes mellitus
pp. 12-12(1)

Prefilled follitropin alfa injection pen gains acceptance
pp. 12-12(1)

Lumiracoxib lightens burden of pain after dental surgery
pp. 12-12(1)

Transdermal oxybutynin improves QOL in men with OAB
pp. 12-12(1)

Vaginal progesterone gel versus IM progesterone in IVF-ET
pp. 13-13(1)

Prophylactic haloperidol prevents PONV after laparoscopic surgery
pp. 13-13(1)

SSRI-to-duloxetine switch a good move in MDD
pp. 13-13(1)

Statins appear to reduce the risk of cancer, particularly lung and colorectal disease, in older adults
pp. 13-13(1)

Thrombolysis appears to improve outcomes in patients with ischaemic strokes after cardiac catheterisation
pp. 14-14(1)

Serving up an ACE inhibitor may prevent cancer
pp. 14-14(1)

Metoclopramide has head start on hydromorphone for migraine
pp. 14-14(1)

Pregabalin may be an effective treatment for trigeminal neuralgia
pp. 14-14(1)

Telbivudine trumps lamivudine for Chinese with chronic hep B
pp. 14-14(1)

Paroxetine "not superior" to placebo in major depression
pp. 15-15(1)

Vasopressin and norepinephrine are comparable for the treatment of patients with septic shock
pp. 15-15(1)

High concentration lidocaine is effective for the treatment of trigeminal neuralgia.
pp. 15-15(1)

Step-down therapy takes a bite out of rheumatoid arthritis
pp. 15-15(1)

Meningococcal serogroup C vax reduces carriage
pp. 15-15(1)

Estradiol/dydrogesterone increases ghrelin-stimulated growth hormone (GH) secretion in postmenopausal women.
pp. 16-16(1)

Levosimendan appears to be beneficial for patients with ischaemic heart failure
pp. 16-16(1)

Oral fluconazole appears to have a greater impact than IV fluconazole on the interaction with calcineurin inhibitors that are given by continuous IV infusion
pp. 16-16(1)

Local anaesthetics may be useful in suppressing inflammatory response and preventing postoperative hyperalgesia
pp. 16-16(1)

Health Canada has completed its safety review of esomeprazole [Nexium] and omeprazole [Losec].
pp. 16-16(1)

Dacart development terminated; Lapdap recalled
pp. 16-16(1)

Tysabri label update: liver injury
pp. 17-17(1)

Abarelix [Plenaxis] launched in Germany.
pp. 17-17(1)

Actavis has received approval for four generics in the US.
pp. 17-17(1)

Abbreviated New Drug Application approved for carbinoxamine in US.
pp. 17-17(1)

Fluvoxamine once-daily formulation approved in the US.
pp. 17-17(1)

Rilonacept approved in US for CAPS in adults and kids
pp. 17-17(1)

Good news for desvenlafaxine in major depressive disorder
pp. 17-17(1)

EUR 1008 granted priority review by the US FDA.
pp. 17-17(1)

Levofloxacin inhalation solution granted orphan drug status in the US.
pp. 17-17(1)

Multiple companies receive approval for irinotecan in US.
pp. 18-18(1)

Tolvaptan application accepted by EMEA.
pp. 18-18(1)

New Drug Application granted priority review for difluprednate in US.
pp. 18-18(1)

Lidocaine/tetracaine has been granted marketing authorisation in Europe
pp. 18-18(1)

US FDA approves esomeprazole for GERD in kids
pp. 18-18(1)

The US FDA has approved aripiprazole
pp. 18-18(1)

Trastuzumab approved for new indication in Japan.
pp. 18-18(1)

Palonosetron approved for PONV in US.
pp. 18-18(1)

The US FDA has granted priority review for eltrombopag
pp. 18-18(1)

Omeprazole 20mg delayed-release tablets launched in the US.
pp. 18-18(1)

US FDA issues not approvable letter for istradefylline.
pp. 19-19(1)

US FDA issues not approvable letter for olanzapine
pp. 19-19(1)

US FDA grants priority review to rabeprazole
pp. 19-19(1)

Verapamil receives Japanese approval for additional indications
pp. 19-19(1)

Urocidin receives fast track designation in the US.
pp. 19-19(1)