Inpharma

GPIIb-IIIa antagonists: upstream vs deferred use in acute coronary syndromes
pp. 1-1(1)

US recommended paediatric immunisation schedules updated
pp. 2-2(1)

Is current spending on HIV/AIDS justified?
pp. 2-2(1)

Prototype pandemic influenza vaccines against avian influenza strains appear promising, but production capacity for these agents remains low
pp. 2-2(1)

The regulatory obstacles hindering antibacterial development
pp. 3-3(1)

Torcetrapib termination has widespread ramifications
pp. 3-3(1)

When the evidence is strong enough without randomisation
pp. 3-3(1)

Acupuncture "relatively cost-effective" for chronic neck pain
pp. 4-4(1)

Pneumococcal vaccination worth it for the elderly in Italy?
pp. 4-4(1)

PHARMAC defends cautious approach over trastuzumab
pp. 4-4(1)

Cetuximab + radiotherapy good value for head and neck cancer
pp. 5-5(1)

Total costs of care, QOL in patients with AD and their carers
pp. 5-5(1)

Pregabalin superior for neuropathic pain
pp. 5-5(1)

Rapid anticoagulant effect with otamixaban in CAD
pp. 6-6(1)

Ostabolin has "potential . . . as an agent that can rapidly increase bone mass" in postmenopausal women with osteoporosis
pp. 6-6(1)

Pumosetrag [DDP 733] may be an effective treatment for patients with irritable bowel syndrome (IBS) with constipation
pp. 6-6(1)

Bavituximab has shown potential in the treatment of patients with chronic hepatitis C virus infection
pp. 6-6(1)

BACH results music to the ears of patients with hand dermatitis
pp. 6-6(1)

Heparin prolongs the usability of peripherally placed percutaneous central venous catheters (PCVC) in neonates
pp. 7-7(1)

S-1 is beneficial for colorectal and gastric cancer
pp. 7-7(1)

Live attenuated flu vax compared with inactivated version in kids
pp. 7-7(1)

The addition of an antipsychotic appears to improve the response rate in patients with obsessive-compulsive disorder (OCD)
pp. 8-8(1)

Two artesunate-based therapies for malaria are also effective in the treatment of schistosomiasis in children
pp. 8-8(1)

Tinzaparin another therapeutic option for recurrent VTE
pp. 8-8(1)

Midodrine appears to be effective in the treatment of children and adolescents with vasovagal syncope
pp. 8-8(1)

Polypill puts pressure on monotherapy for hypertension
pp. 8-8(1)

Clindamycin/tretinoin combo clearly more effective in acne vulgaris
pp. 9-10(2)

Diclofenac hydroxyethylpyrrolidine for acute migraine
pp. 10-10(1)

Clopidogrel not enough for some coronary stent recipients?
pp. 11-11(1)

IV paracetamol is comparable to oral ibuprofen in the management of pain after a caesarean section
pp. 11-11(1)

Erdosteine a breath of fresh air for kids with respiratory infection
pp. 11-11(1)

Rosiglitazone combined with fenofibrate appears to be more beneficial than rosiglitazone in patients with type 2 diabetes mellitus
pp. 11-11(1)

Pegylated liposomal doxorubicin plus carboplatin is an effective treatment for advanced ovarian cancer
pp. 11-11(1)

Calcipotriol/betamethasone dipropionate a success in scalp psoriasis
pp. 13-14(2)

In elderly patients with poor-prognosis acute myeloid leukaemia (AML), filgrastim may be a beneficial adjunct to supportive care
pp. 14-14(1)

Eptacog-α and factor VIII inhibitor bypassing fraction (FEIBA) may be comparable in the treatment of patients with haemophilia A with inhibitors
pp. 14-14(1)

Tibolone is more effective than estradiol in the treatment of climacteric symptoms due to surgical menopause
pp. 14-14(1)

Adding methylprednisolone to conventional therapy for the treatment of Kawasaki's syndrome provides little additional benefit
pp. 15-15(1)

Tadalafil improves erectile dysfunction (ED) in men receiving antidepressant medication
pp. 15-15(1)

The combination of cyclophosphamide, thalidomide and dexamethasone may be an effective treatment for systemic light-chain amyloidosis
pp. 15-15(1)

Almotriptan and zolmitriptan have similar efficacy in the acute treatment of migraine, although almotriptan is better tolerated
pp. 15-15(1)

Lenalidomide with or without dexamethasone in amyloidosis
pp. 15-15(1)

Tick-borne encephalitis vaccination schedules compared
pp. 16-16(1)

Cefdinir and cefalexin have comparable efficacy for uncomplicated skin and skin structure infections (USSSIs) in adults and adolescents
pp. 16-16(1)

Continuous IV cefotaxime may be more effective than intermittent administration for the treatment of respiratory tract infections
pp. 16-16(1)

Sevoflurane a possible alternative to nitrous oxide during labour
pp. 16-16(1)

Efalizumab's efficacy in psoriasis extends to the extremities
pp. 17-18(2)

In patients with atrial fibrillation, warfarin therapy commenced prior to detection of left atrial thrombus (LAT) reduces the incidence of stroke
pp. 18-18(1)

Gemcitabine plus treosulfan is more effective than treosulfan alone in metastatic uveal melanoma
pp. 18-18(1)

Prior influenza vaccination reduces the mortality rate for patients hospitalised with community acquired pneumonia
pp. 18-18(1)

Ketamine prevents shivering during regional anaesthesia
pp. 18-18(1)

Antipsychotics enhance mood stabilisers for bipolar mania
pp. 18-18(1)

Omeprazole provides more durable control of gastric acidity than famotidine
pp. 19-19(1)

Pyrimethamine/sulfadoxine: effect of PK on dosing in paeds
pp. 19-19(1)

The combination of lenalidomide and pegylated liposomal doxorubicin-based chemotherapy may be effective for the treatment of multiple myeloma
pp. 19-19(1)

Disufenton [NXY 059] does not affect primary haemostasis in healthy volunteers
pp. 19-19(1)

A once-daily formulation of tramadol has demonstrated efficacy for pain in patients with knee osteoarthritis
pp. 19-19(1)

Erythropoietins: mortality warning extends to use in cancer
pp. 20-20(1)

Tumour concentrations of paclitaxel are markedly increased when it is administered with a cholesterol-rich nanoemulsion (LDE) in women with gynaecologic cancer
pp. 20-20(1)

Possible link between RotaTeq and intussusception
pp. 20-20(1)

Human hyaluronidase [Hylenex] reduces the time to peak plasma concentration of SC morphine
pp. 20-20(1)

Drug-eluting stents: utmost restraint recommended in Sweden
pp. 21-21(1)

Alopecia linked to quetiapine
pp. 21-21(1)

No surprises with switch from DT to DTaP vaccine
pp. 22-22(1)

Other US regulatory news
pp. 22-22(1)

US product approvals
pp. 22-22(1)

The US prescribing information for RotaTeq [rotavirus W179-9 vaccine] has been updated
pp. 22-22(1)

A number of Americans who ordered drugs via the internet received mislabeled products that, according to preliminary analyses, contained haloperidol
pp. 22-22(1)

The UK MHRA has advised that it is aware of six cases of heavy metal poisoning associated with use of Ayurvedic medicines
pp. 22-22(1)

Regulatory news from Japan
pp. 23-23(1)

A generic version of the cholesterol-lowering drug atorvastatin has been launched in Denmark by Ranbaxy Laboratories.
pp. 23-23(1)

The European Medicines Evaluation Agency will grant an accelerated review of Pfizer's marketing authorisation application for maraviroc.
pp. 23-23(1)

Tibotec Pharmaceuticals' protease inhibitor darunavir [PREZISTA] has received conditional marketing authorisation from the European Commission
pp. 23-23(1)

FAES Farma has launched a once-daily formulation of troxerutin [Esberiven] for circulatory disorders of venous origin, in Spain.
pp. 23-23(1)