Inpharma

Clinical trial registration: the debate continues . . .
pp. 2-2(1)

WHO warning over artemisinin monotherapy may be working
pp. 2-2(1)

For-profit funding favours favourable findings
pp. 2-2(1)

Investment in clinical trials "well justified"
pp. 3-3(1)

Mandatory influenza vaccinations for health care workers: yes or no?
pp. 3-3(1)

Recent research indicates that drug-based therapy for aortic aneurysms is a real possibility
pp. 3-3(1)

Hospitalisation, complications, raise treatment cost of type 2 diabetes
pp. 4-4(1)

High-dose mesalazine a gutsy choice
pp. 4-4(1)

SLE in children a considerable cost burden in the US
pp. 4-4(1)

Losartan cost effective in hypertension with LVH
pp. 5-5(1)

Utilisation of healthcare services reduced in the uninsured
pp. 5-5(1)

Regional efforts could improve vax programme efficiency
pp. 5-5(1)

Topiramate/phentermine combination effective for obesity
pp. 6-6(1)

Leuprorelin stabilises cognition in women with Alzheimer's disease
pp. 6-6(1)

Ispronicline promising for the treatment of memory disorders
pp. 6-6(1)

VX 950 in combination with peginterferon-α-2a and ribavirin has strong antiviral activity in patients with hepatitis C
pp. 6-6(1)

Certolizumab pegol [Cimzia] is effective for patients with moderate-to-severe Crohn's disease
pp. 6-6(1)

Verapamil SR + trandolapril for high-risk Hispanic patients
pp. 7-7(1)

Sugammadex effectively reverses rocuronium-induced neuromuscular (NM) block
pp. 7-7(1)

Pamidronic acid cessation effects in paediatric osteogenesis imperfecta
pp. 7-7(1)

Treatment with NX 1207 for benign prostatic hyperplasia (BPH) may provide long-term efficacy
pp. 7-7(1)

HER2 predicts response to an anthracycline-containing regimen
pp. 8-8(1)

Nitroglycerin plus dinoprostone is more effective for labour induction than dinoprostone alone
pp. 8-8(1)

Long-acting octreotide promising primary therapy for acromegaly
pp. 8-8(1)

Tegaserod may be an effective treatment for women with irritable bowel syndrome (IBS) exhibiting a mixed bowel pattern
pp. 8-8(1)

Moxifloxacin monotherapy on par with combination therapy in CAP
pp. 9-10(2)

Caffeine citrate beneficial for premature neonates
pp. 11-11(1)

Tolvaptan is more effective than fluid restriction in patients with hyponatraemia
pp. 11-11(1)

WOCA regimen prevents UTI in spinal cord injury
pp. 11-11(1)

Olanzapine/fluoxetine improves the symptoms of bipolar I depression more effectively than lamotrigine
pp. 11-11(1)

Aspirin plus dipyridamole effective in secondary stroke prevention
pp. 12-12(1)

Policosanol has similar efficacy to placebo in reducing LDL-cholesterol levels in patients with hyperlipidaemia
pp. 12-12(1)

Oral better than IV patient-controlled analgesia after caesarean
pp. 12-12(1)

Paracetamol [acetaminophen] plus ketoprofen reduces morphine requirements in postoperative paediatric patients
pp. 12-12(1)

Reboxetine is an effective alternative in the treatment of post-traumatic stress disorder (PTSD) related to motor vehicle accidents
pp. 12-12(1)

Early almotriptan intervention ameliorates migraine symptoms
pp. 13-14(2)

Mesalazine and Lactobacillus casei, alone or in combination, prevent recurrence of symptomatic uncomplicated diverticular colon disease
pp. 15-15(1)

Long-term rivastigmine effective for dementia associated with PD
pp. 15-15(1)

Augmentation of serotonin reuptake inhibitor (SSRI) treatment with liothyronine may be effective for patients with depression
pp. 15-15(1)

Fosamprenavir + ritonavir similar to lopinavir/ritonavir in HIV
pp. 15-15(1)

Rifaximin alone or in combination with loperamide is an effective treatment for traveller's diarrhoea
pp. 15-15(1)

Pyridoxine and mianserin may improve acute NIA
pp. 16-16(1)

Infliximab added to AZA or 6-MP helps in Crohn's disease
pp. 16-16(1)

Oxandrolone added to gonadotropin-releasing hormone agonist (GnRHa) treatment improves final height in girls
pp. 16-16(1)

Sedation with propofol, interrupted daily, results in fewer ventilator days than intermittent lorazepam and may improve ventilator-free survival
pp. 16-16(1)

A paclitaxel-eluting coronary stent has demonstrated a sustained long-term reduction of revascularisation rates in high-risk patients
pp. 16-16(1)

Consistent colorectal cancer prevention with celecoxib
pp. 17-18(2)

Olmesartan medoxomil/HCTZ beneficial in hypertension
pp. 19-19(1)

Metformin XR effective in type 2 diabetes
pp. 19-19(1)

Sequential carboplatin-based chemo for ovarian cancer
pp. 19-19(1)

Antifungal prophylaxis effective for critically ill patients
pp. 19-19(1)

Ondansetron readily crosses the placenta in the first trimester of pregnancy
pp. 20-20(1)

Intrarenal fenoldopam may protect against contrast nephropathy
pp. 20-20(1)

GH replacement benefits cardiac morphology in children
pp. 20-20(1)

Tequin: labelling updated in Canada
pp. 21-21(1)

Reminder: monitor women exposed in utero to diethylstilbestrol
pp. 21-21(1)

Health Canada is advising patients who have previously had a myocardial infarction (MI) to not use arginine supplements
pp. 21-21(1)

US product approvals
pp. 22-22(1)

Other US regulatory news
pp. 22-22(1)

Does the CV risk with Vioxx elevate earlier than reported?
pp. 22-22(1)

EU product approvals
pp. 23-23(1)

Pegaptanib [Macugen], Pfizer's treatment for wet age-related macular degeneration (AMD), has been launched in the UK
pp. 23-23(1)

Pfizer Canada's exemestane [Aromasin] tablets have been granted a Notice of Compliance with Conditions by Health Canada.
pp. 23-23(1)