Inpharma

Benefits of immunising children against influenza
pp. 2-2(1)

Maternal, child development goals out of reach?
pp. 2-2(1)

Physician preference outweighs patient risk in NSAID users
pp. 3-3(1)

UK DoH could overturn NICE provisional Alzheimer's decision
pp. 3-3(1)

Taking from the rich to give to the poor benefits both
pp. 3-3(1)

Re-approval of Vioxx [rofecoxib] requires additional US FDA committee consideration
pp. 3-3(1)

Myeloid Growth Factors guidelines have been released by the US National Comprehensive Cancer Network
pp. 3-3(1)

Sivelestat cost saving for acute lung injury in Japan
pp. 4-4(1)

Recommendations for the management of chronic abdominal pain in paediatric individuals have been issued by the Subcommittee on Abdominal Pain
pp. 4-4(1)

Hyperbilirubinaemia management guidelines discussed
pp. 4-4(1)

Routine use of recombinant erythropoietin (EPO) to reduce the need for blood transfusions in critically-ill patients is not considered an efficient use of limited resources
pp. 4-4(1)

Empirical methotrexate not ideal for suspected ectopic pregnancy
pp. 5-5(1)

Rosuvastatin STELLAR option for lowering LDL-cholesterol
pp. 5-5(1)

Drotrecogin alfa "cost effective option" in severe sepsis in the UK
pp. 5-5(1)

Zoledronic acid, pamidronic acid on equal footing in bone metastases
pp. 6-6(1)

Costs no higher with everolimus in heart transplant
pp. 6-6(1)

Aliskiren may lower BP in hypertension
pp. 7-7(1)

rhAT may restore heparin responsiveness
pp. 7-7(1)

Infliximab may be effective for sight-threatening diabetic macular oedema
pp. 7-7(1)

Prophylactic ubidecarenone [coenzyme Q10] may be effective in patients with migraine
pp. 7-7(1)

Ularitide may be a hearty treatment for decompensated congestive heart failure
pp. 7-7(1)

R&D news from ECCMID
pp. 8-9(2)

Neoadjuvant trastuzumab + FEC for HER2-positive breast cancer
pp. 9-9(1)

Lovastatin warrants further investigation in patients with recurrent or metastatic head and neck or cervical cancer
pp. 9-9(1)

MMF reverses `creeping creatinine' after renal transplant
pp. 9-9(1)

"End of the road" for azithromycin, gatifloxacin in CAD, ACS
pp. 10-10(1)

Gepirone ER extends remission in recurrent depression
pp. 10-10(1)

Estradiol/levonorgestrel boosts BMD in postmenopausal women
pp. 10-10(1)

Lorazepam alone, or with the addition of diazepam "could rapidly relieve catatonic signs in patients with schizophrenia"
pp. 10-10(1)

Legs can rest easy with pramipexole
pp. 11-12(2)

No bones about it: methotrexate, leflunomide effective in JRA
pp. 12-12(1)

Flutamide with or without citalopram may reduce binge eating in women with bulimia nervosa
pp. 12-12(1)

Treatment with venlafaxine extended-release (ER) decreases Liebowitz Social Anxiety Scale (LSAS) scores in patients with social phobia
pp. 12-12(1)

Three-dose PCV7 vaccine immunogenic in infants
pp. 13-13(1)

Anastrozole may induce remission in Waldenström's macroglobulinaemia
pp. 13-13(1)

Treatment with metformin may be associated with a reduced risk of cancer in patients with type 2 diabetes mellitus (DM)
pp. 13-13(1)

Fluvastatin after PCI counteracts the effect of renal impairment
pp. 13-13(1)

Valaciclovir for CMV prophylaxis reduces risk of acute rejection
pp. 13-13(1)

Bortezomib shows potential in NHL
pp. 14-14(1)

Flu vax worth it for high-risk patients of all ages
pp. 14-14(1)

Dalteparin efficacious in patients with obesity, elderly
pp. 14-14(1)

Low-dose doxepin is effective in the treatment of primary chronic sleep maintenance insomnia in elderly patients
pp. 14-14(1)

Pioglitazone: post-stenting benefits in patients without diabetes
pp. 15-16(2)

Rhabdomyosarcoma cure without local therapy?
pp. 16-16(1)

Misoprostol provides benefit for labour induction
pp. 16-16(1)

Carvedilol ices metoprolol tartrate in chronic heart failure
pp. 18-18(1)

Mifepristone + at-home misoprostol effective for medical abortion
pp. 18-18(1)

Infliximab is effective in patients with persistent and refractory polyarticular-course juvenile rheumatoid arthritis (JRA)
pp. 18-18(1)

Single-dose azithromycin challenges amoxicillin for acute OM
pp. 18-18(1)

Pravastatin may be effective in patients with treatment-refractory chronic graft-versus-host disease (GVHD) following allogenic haematopoietic stem cell transplantation
pp. 18-18(1)

Pioglitazone, gliclazide: equivalent HbA1c reductions in type 2 diabetes
pp. 19-19(1)

Analgesic potency of bupivacaine > levobupivacaine > ropivacaine
pp. 19-19(1)

The pharmacokinetics of methadone are not affected by concurrent administration with peginterferon--2a in hepatitis C virus (HCV) infection
pp. 19-19(1)

MPA exposure too variable in fixed-dose MMF recipients
pp. 19-19(1)

EMEA concludes SSRIs and SNRIs not for use in children, adolescents
pp. 20-20(1)

Pooled analysis shows increased mortality with nesiritide
pp. 20-20(1)

NSAID use may increase risk of acute renal failure
pp. 20-20(1)

Torsade de pointes risk with psychotropics seen in a heart beat
pp. 20-20(1)

Amoxicillin/clavulanic acid [Co-amoxiclav] appears to be associated with more reports of serious adverse events than amoxicillin in Italy
pp. 20-20(1)

In utero valproic acid exposure may increase risk of congenital disorders
pp. 21-21(1)

US generic approvals
pp. 21-21(1)

European product approvals
pp. 22-22(1)

EU product launches
pp. 22-22(1)

Other EU regulatory news
pp. 22-22(1)

Product approvals in Canada
pp. 22-22(1)

Other US regulatory news
pp. 22-22(1)

Carbamazepine extended-release capsules [Equetro; Shire Pharmaceuticals Group] are now available in the US
pp. 22-22(1)

Ethinylestradiol/desogestrel [Marvelon 21; Nippon Organon] has been launched in Japan.
pp. 22-22(1)

Natural interferon- [Multiferon; Viragen] has been approved in the Philippines.
pp. 22-22(1)

Product Introductions
pp. 23-23(1)