Nitazoxanide: A Review of its Use in the Treatment of Gastrointestinal Infections

Authors: Anderson, Vanessa R.; Curran, Monique P.

Source: Drugs, Volume 67, Number 13, 2007 , pp. 1947-1967(21)

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Abstract:

Nitazoxanide (Alinia^®, Daxon^®, Dexidex^®, Paramix^®, Kidonax^®, Colufase^®, Annita^®) has in vitro activity against a variety of microorganisms, including a broad range of protozoa and helminths. Nitazoxanide is effective in the treatment of protozoal and helminthic infections, including Cryptosporidium parvum or Giardia lamblia, in immunocompetent adults and children, and is generally well tolerated. Nitazoxanide is a first-line choice for the treatment of illness caused by C. parvum or G. lamblia infection in immunocompetent adults and children, and is an option to be considered in the treatment of illnesses caused by other protozoa and/or helminths.

Keywords: Adis Drug Evaluations; Diarrhoea; Helminthiasis; Nitazoxanide; Protozoal infections

Document Type: Research article

Affiliations: 1: Wolters Kluwer Health | Adis, Auckland, New Zealand, an editorial office of Wolters Kluwer Health, Conshohocken, Pennsylvania, USA

Publication date: 2007-01-01