@article {Oldfield:2005:0012-6667:2337,
	author = "Oldfield, Vicki",
	author = "Perry, Caroline M.",
	title = "Oxycodone/Ibuprofen Combination Tablet: A Review of its Use in the Management of Acute Pain",
	journal = "Drugs",
	volume = "65",
	year = "2005",
	abstract = "Oxycodone/ibuprofen 5mg/400mg (Combunox&#8482;) is an oral fixed-dose combination tablet with analgesic, anti-inflammatory and antipyretic properties. It is approved in the US for the short-term (up to 7 days) management of acute, moderate-to-severe pain and is the first and only fixed-dose combination containing ibuprofen and oxycodone.<P></P>A single dose of oxycodone/ibuprofen 5mg/400mg provided better analgesia than low-dose oxycodone or ibuprofen administered alone in most trials and appears to be more effective than a single dose of some other fixed-dose combination analgesics. It is generally well tolerated after single or multiple doses and short-term use is not expected to produce any of the serious adverse effects typically associated with the long-term use of opioids or NSAIDs. Thus, oxycodone/ibuprofen 5mg/400mg is an effective, convenient treatment option for the short-term management of acute, moderate-to-severe pain.",
	pages = "2337-2354(18)",
	url = "http://www.ingentaconnect.com/content/adis/dgs/2005/00000065/00000016/art00011"
}