@article {Frigas:3 June 2009:1175-0561:239,
	author = "Frigas, Evangelo",
	author = "Park, Miguel A.",
	title = "Acute Urticaria and Angioedema: Diagnostic and Treatment Considerations",
	journal = "American Journal of Clinical Dermatology",
	volume = "10",
	year = "3 June 2009",
	abstract = "Urticaria is defined as wheals consisting of three features: (i) central swelling of various sizes, with or without surrounding erythema; (ii) pruritus or occasional burning sensations; and (iii) the skin returning to normal appearance, usually within 1-24 hours. Angioedema is defined as: (i) abrupt swelling of the lower dermis and subcutis; (ii) occasional pain instead of pruritus; (iii) commonly involving the mucous membranes; and (iv) skin returning to normal appearance, usually within 72 hours. Acute urticaria and angioedema is defined by its duration (<6 weeks) compared with chronic urticaria and angioedema. The most common causes are infections, medications, and foods. The best tools in the evaluation of these patients are a comprehensive history and physical examination. There are a variety of skin conditions that may mimic acute urticaria and angioedema and the various reaction patterns associated with different drugs. Oral antihistamines are first-line treatment. In the event of a life-threatening reaction involving urticaria with angioedema, epinephrine may be needed to stabilize the patient. This review focuses on the value of a comprehensive clinical evaluation at the onset of symptoms. It underscores the importance of coordination of care among physicians, and the development of an action plan for evidence-based investigations, diagnosis, and therapy.",
	pages = "239-250(12)",
	url = "http://www.ingentaconnect.com/content/adis/derm/2009/00000010/00000004/art00004"
}