Bimatoprost/Timolol: A Review of Its Use in Glaucoma and Ocular Hypertension

Authors: Curran, Monique P.; Orman, Jennifer S.

Source: Drugs & Aging, Volume 26, Number 2, 2009 , pp. 169-184(16)

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Abstract:

Topically administered bimatoprost 0.03%/timolol 0.5% ophthalmic solution (bimatoprost/timolol: Ganfort^®) comprises the synthetic prostamide bimatoprost (structurally related to prostaglandin F_2α) and the β-adrenergic receptor antagonist timolol.

Bimatoprost/timolol (one drop administered in the affected eye[s] once daily in the morning or evening) is an effective and well tolerated fixed combination for lowering intra-ocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT), including individuals uncontrolled on monotherapy with a ß-adrenergic receptor antagonist or prostaglandin analogue/prostamide.

Keywords: Adis Drug Evaluations; Bimatoprost/timolol; Bimatoprost/timolol; Bimatoprost/timolol; Glaucoma; Research and development

Document Type: Research article

Affiliations: 1: Wolters Kluwer Health | Adis, Auckland, New Zealand, an editorial office of Wolters Kluwer Health, Conshohocken, Pennsylvania, USA

Publication date: 2009-01-01