An Update on the Functional Molecular Immunology (FIMM) Database

Authors: Schönbach, Christian; Koh, Judice L.Y.¹; Flower, Darren R.²; Brusic, Vladimir

Source: Applied Bioinformatics, Volume 4, Number 1, 2005 , pp. 25-31(7)

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Abstract:

Data on the major histocompatibility complex, T-cell epitopes, B-cell epitopes, antigens and diseases are heterogeneous and scattered among different databases and the literature. Since it has become increasingly difficult to obtain an integrated view of functional immune response components, we have developed and updated over several years the Functional molecular IMMunology (FIMM) database (http:// research.i2r.a-star.edu.sg/fimm/). FIMM contains integrated expert-curated data on protein antigens, and on human immunological receptors that recognise and bind them in healthy or disease states. Interfaces with multiple, intuitive query options and query reports provide immunologists with prioritised information that aids data interpretation, vaccine target discovery and immune disease research.

Keywords: Allergy and Immunology; Bioinformatics; Genomics; HLA antigens; T cell receptor

Document Type: Research article

Affiliations: 1: 1 Knowledge Discovery Department, Institute for Infocomm Research, Singapore 2: 3 The Edward Jenner Institute for Vaccine Research, Compton, UK

Publication date: 2005-01-01