Localized Unilateral Periorbital Edema Induced by Aspirin

Authors: Price, Kursteen S.; Thomson, David M.P.

Source: Annals of Allergy, Asthma and Immunology, Volume 79, Number 5, November 1997 , pp. 420-422(3)

Publisher: American College of Allergy, Asthma, & Immunology

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Abstract:

Background: Aspirin intolerance manifested as bronchospasm or urticaria/angioedema has been observed since the beginning of this century.

Objective: To report a novel case of intolerance to aspirin ingestion.

Methods: Case report; routine skin testing; pulmonary function testing; aspirin challenge.

Results: A 30-year-old man with a history of left ocular trauma at the age of 10 noted a 3-year history of left periorbital angioedema after aspirin but not other nonsteroidal anti-inflammatory drugs. Incremental oral aspirin challenge resulted in this unilateral symptomatology at a dose of 673 mg.

Conclusion: To the best of our knowledge, this is the first reported case of unilateral periorbital edema following aspirin ingestion.

Document Type: Research article

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