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Vitamin D and Dental Caries in Primary Dentition

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Traditionally classified as a vitamin, vitamin D represents a group of fat-soluble secosteroids with D2 (ergocalciferol) and D3 (cholecalciferol) being the most relevant of the group. The importance of this prohormone exceeds its known ability to maintain intra- and extracellular calcium and phosphate concentrations, thereby preserving essential metabolic functions such as the promotion of mineralization and maintenance and remodeling of the bone. Current observational research recognizes the potential antiproliferative, prodifferentiative, and immunomodulatory effects of vitamin D and its metabolites in the human body. The purposes of this paper are to: (1) review how vitamin D interacts in the body, its deficiency at the population level, and how it relates to oral health in children; and (2) assess proposed biological mechanisms by which vitamin D may play a preventive role in the development of dental caries.
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Keywords: CARIES DETECTION/DIAGNOSIS/PREVENTION; PREVENTIVE DENTISTRY; SALIVARY ANTIMICROBIAL PROTEINS; VITAMIN D

Document Type: Research Article

Affiliations: 1: Assistant professors, Department of Pediatric Dentistry, University of Washington, Seattle, Wash., USA;, Email: alsadem@uw.edu 2: Assistant professors, Department of Pediatric Dentistry, University of Washington, Seattle, Wash., USA

Publication date: 2016-09-01

More about this publication?
  • Acquired after the merger between the American Society of Dentistry for Children and the American Academy of Pediatric Dentistry in 2002, the Journal of Dentistry for Children (JDC) is an internationally renowned journal whose publishing dates back to 1934. Published three times a year, JDC promotes the practice, education and research specifically related to the specialty of pediatric dentistry. It covers a wide range of topics related to the clinical care of children, from clinical techniques of daily importance to the practitioner, to studies on child behavior and growth and development. JDC also provides information on the physical, psychological and emotional conditions of children as they relate to and affect their dental health.
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