Gingival Overgrowth in a Renal Transplant Recipient Using Cyclosporine A

Authors: Gonçalves, Soraya Cheier Dib¹; Díaz-Serrano, Kranya Victoria¹; de Queiroz, Alexandra Mussolino¹; Palioto, Daniela Bazan²; Faria, Gisele³

Source: Journal of Dentistry for Children, Volume 75, Number 3, September-December 2008 , pp. 313-317(5)

Publisher: American Academy of Pediatric Dentistry

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Abstract:

Unsightly gingival enlargement is a frequent side effect in organ transplant recipients under immunosuppressive therapy with cyclosporin A (CsA). The purpose of this article was to report the treatment management of cyclosporin A-induced gingival overgrowth in a 9-year-old renal transplant recipient. Surgical reduction of the overgrown gingival tissue associated with an intensive biofilm control program and conversion from CsA to tacrolimus provided good clinical outcome with improvement of mastication, feeding, and phonetics. Gingival overgrowth stabilized with the change of medication. After approximately 3 months of follow-up, a regression of gingival enlargement was observed.

Keywords: CYCLOSPORIN A; GINGIVAL OVERGROWTH; COMBINED MODALITY THERAPY; RENAL TRANSPLANT

Document Type: Case report

Affiliations: 1: Department of Pediatric Clinics, Preventive and Social Dentistry, School of Dentistry of Ribeirão Preto, University of Sao Paulo, Ribeirão Preto, Sao Paulo, Brazil 2: Department of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of Sao Paulo, Ribeirão Preto, Sao Paulo, Brazil 3: Department of Pathology, Medical School of Ribeirão, Preto, University of São Paulo, Ribeirão Preto

Publication date: 2008-09-01

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Acquired after the merger between the American Society of Dentistry for Children and the American Academy of Pediatric Dentistry in 2002, the Journal of Dentistry for Children (JDC) is an internationally renowned journal whose publishing dates back to 1934. Published three times a year, JDC promotes the practice, education and research specifically related to the specialty of pediatric dentistry. It covers a wide range of topics related to the clinical care of children, from clinical techniques of daily importance to the practitioner, to studies on child behavior and growth and development. JDC also provides information on the physical, psychological and emotional conditions of children as they relate to and affect their dental health.
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Gingival Overgrowth in a Renal Transplant Recipient Using Cyclosporine A

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