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Open Access Intracranial Meningioma with Ophthalmoplegia in a Rhesus Macaque (Macaca mulatta)

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A 21-y-old female rhesus macaque presented with signs of internal and external ophthamoplegia, including anisocoria and ptosis. Ophthalmoplegia is the paralysis or weakness of one or more intraocular or extraocular muscles that control the movement of eye; this condition can be caused by neurologic or muscle disorders. The macaque was euthanized due to progression of clinical symptoms, and postmortem gross examination revealed a mass at the base of the brain attached to the meninges. Histopathologic examination led to the diagnosis of intracranial meningioma. Here we describe a case of intracranial meningioma with internal and external ophthalmoplegia in a rhesus macaque (Macaca mulatta).

Document Type: Case Report

Affiliations: 1: California National Primate Research Center, School of Veterinary Medicine, University of California Davis, Davis, California, USA; New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, USA. 2: California National Primate Research Center, School of Veterinary Medicine, University of California Davis, Davis, California, USA

Publication date: October 1, 2012

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  • Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.

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