Open Access

Cerebrovascular Accident (Stroke) in Captive, Group-Housed, Female Chimpanzees

Authors: Jean, Sherrie M1; Preuss, Todd M2; Sharma, Prachi3; Anderson, Daniel C3; Provenzale, James M4; Strobert, Elizabeth5; Ross, Stephen R6; Stroud, Fawn C5

Source: Comparative Medicine, Volume 62, Number 4, August 2012 , pp. 322-329(8)

Publisher: American Association for Laboratory Animal Science

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Abstract:

Over a 5-y period, 3 chimpanzees at our institution experienced cerebrovascular accidents (strokes). In light of the increasing population of aged captive chimpanzees and lack of literature documenting the prevalence and effectiveness of various treatments for stroke in chimpanzees, we performed a retrospective review of the medical records and necropsy reports from our institution. A survey was sent to other facilities housing chimpanzees that participate in the Chimpanzee Species Survival Plan to inquire about their experience with diagnosing and treating stroke. This case report describes the presentation, clinical signs, and diagnosis of stroke in 3 recent cases and in historical cases at our institution. Predisposing factors, diagnosis, and treatment options of cerebral vascular accident in the captive chimpanzee population are discussed also.

Document Type: Case Report

Affiliations: 1: Department of Animal Resources, School of Medicine, Emory University, Atlanta, Georgia, USA. sherriej@med.usc.edu 2: Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA 3: Division of Pathology, Yerkes National Primate Research Center, School of Medicine, Emory University, Atlanta, Georgia, USA 4: Radiology and Imaging Sciences, School of Medicine, Emory University, Atlanta, USA 5: Department of Animal Resources, School of Medicine, Emory University, Atlanta, Georgia, USA 6: Lester E Fisher Center for the Study and Conservation of Apes, Lincoln Park Zoo, Chicago, Illinois

Publication date: August 1, 2012

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  • Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.

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