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Open Access Use of 18F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in a Miniature Pig (Sus scrofa domestica) with Pneumonia

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A 1-y-old male miniature pig housed in our laboratory facility was evaluated for weight loss and rough coat condition. CBC results revealed neutrophilia. Radiography of the thoracic area showed increased opacity throughout the thoracic cavity except for the right caudal lobe. 18F-labeled fluorodeoxyglucose positron emission tomography–computed tomography (FDG-PET–CT) revealed elevated standard uptake values in the area corresponding to the radiologic findings. Follow-up thoracic radiography taken 2 wk after FDG-PET–CT showed several interval changes, including markedly decreased opacity throughout the entire thoracic cavity. Necropsy revealed adhesions between the upper portion of the caudal lobe of the left lung and thoracic wall. ELISA for several closely related infectious species confirmed the presence of antibody to Actinobacillus pleuropneumoniae serovar V.

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Document Type: Case Report

Affiliations: 1: Department of Laboratory Animal Medicine & Institute for the 3Rs, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea 2: Department of Biochemistryand Molecular Cell Biology, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea. 3: Department of Nuclear Medicine, Konkuk Medical Center, Konkuk University, Seoul, Republic of Korea

Publication date: 2012-06-01

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  • Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.

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