Successful Treatment of Idiopathic Dilated Cardiomyopathy in an Adult Chimpanzee (Pan troglodytes)
Abstract:Various congenital and acquired forms of heart disease have been reported in captive lowland gorillas, and heart disease is a major cause of morbidity and mortality in geriatric humans. However, the prevalence of heart disease is unknown in nonhuman great apes species. Indeed, little is known about heart disease in chimpanzees, although the species has been used in research for decades. This report details the clinical presentation and diagnostics (thoracic radiography, electrocardiography, and echocardiography) utilized to diagnose idiopathic dilated cardiomyopathy in a 27-year-old male chimpanzee. Treatment decisions—indicated by followup diagnostics including repeat electrocardiography, echocardiography, and clinical laboratory data—over the 22-month period during which he continues to be treated are described. In addition, electrocardiographic and echocardiographic findings obtained from 20 clinically normal adult (11 female and 9 male) chimpanzees are presented for comparison.
Document Type: Case Report
Affiliations: 1: Section of Clinical Studies, Ryan Veterinary Hospital, University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104 2: Alamogordo Primate Facility, Holloman Air Force Base, Alamogordo, New Mexico 88330-0956
Publication date: February 1, 2005
Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.
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