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Open Access Carcinosarcoma of the Maxilla in a Squirrel Monkey (Saimiri sciureus)

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Abstract:

We present the first, to our knowledge, described case of carcinosarcoma of the maxilla in a squirrel monkey. Carcinosarcomas are rare tumors of the upper aerodigestive tract, and consist of carcinomatous and sarcomatous tissue. Histologic analysis revealed a neoplasm composed of an adenocarcinomatous component (epithelial element) and a mesenchymal component (sarcomatous element). Metastatic growth was documented in the lung tissue and the submandibular lymph node. The histolopathologic findings, the pattern of metastasis, and the clinical progression closely resembled those of carcinosarcoma involving salivary glands in humans.

Document Type: Case Report

Affiliations: 1: Department of Periodontics, University of Maryland Dental School, 666 W. Baltimore St., Baltimore, Maryland 21201 2: Department of Diagnostic Sciences and Pathology Surgery, University of Maryland Dental School, 666 W. Baltimore St., Baltimore, Maryland 21201 3: Veterinary Resources Program, National Institutes of Health, Office of Research Services, P.O. Box 56, Poolesville, Maryland 20837

Publication date: June 1, 2004

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  • Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.

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